Journal of Yeungnam Medical Science

Jei Jun Bae

2 Articles

Two Cases of Extrapelvic endometriosis following Laparoscopy-assisted vaginal hysterectomy and Cesarean section.: Jei Jun Bae, Mi Sun Lim, Min Whan Koh, Tae Hyung Lee, Mi Jin Kim; Yeungnam Univ J Med. 2007;24(1):91-96. Published online June 30, 2007; DOI: https://doi.org/10.12701/yujm.2007.24.1.91

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Extrapelvic endometriosis is a rare disease. The majority of extrapelvic endometriosis cases involve scar tissue following obstetric and gynecologic procedures. We have treated two cases of extrapelvic incisional endometriosis. A 39 year old female patient with cyclic vaginal spotting after laparoscopic assisted vaginal hysterectomy due to uterine myoma and a 35 year old female patient with a painful palpable abdominal mass after cesarean section. Both underwent complete excision and were proven to have endometriosis by pathology. Here we report on both cases and review the medical literatures.

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A Case of Pleural Endometriosis Presented as Right Sided Hemothorax in a Patient Who Underwent Kidney Transplantation
Eun-Hye Shin, Bo-Mi Shin, Yeon-Jung Ha, Il-Young Jang, Ji-Won Jung, Hyung-Jin Cho, Su-Kil Park
Yeungnam University Journal of Medicine.2013; 30(2): 145. CrossRef

The Production Mechanism of TNF-alpha and IL-6 by Group IIA Phospholipase A2.: Jae Hong Ahn, Dae Won Park, Jin Hee Kim, Jei Jun Bae, Yeun Kyoung Bae, Yoon Ki Park; Yeungnam Univ J Med. 2004;21(2):177-190. Published online December 31, 2004; DOI: https://doi.org/10.12701/yujm.2004.21.2.177

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Abstract PDF: BACKGROUND
Secretory phospholipase A2 (sPLA2) are a group of extracellular enzymes that release fatty acids at the sn-2 position of phospholipids. Group IIA sPLA2 (sPLA2-IIA) has been detected in the inflammatory fluids, and its plasma level increases in the inflammatory disease. This study examined the effect of sPLA2-IIA on mouse macropahges in order to investigate the potential mechanism of sPLA2-induced inflammation. MATERIALS AND METHODS: Wild type PLA2 and mutant H48Q PLA2 were purified from HEK293 cells transfected with the corresponding plasmids, and the PLA2 activities were measured using 1-palmitoyl-2-[1- (14) C]linoleoyl-3-phosphatidylethanolamine as substrates. The TNF-alpha and IL-6 released in the supernatants were determined by ELISA. In addition, the TNF-alpha and IL-6 mRNA were analyzed by RT-PCR. RESULTS: sPLA2-IIA stimulated the production of TNF-alpha and IL-6 in a dose- and time-dependent manner. In addition, the effect of sPLA2-IIA on cytokine production from the macrophage was found to be associated with the accumulation of their specific mRNA. The mRNA levels of TNF-alpha and IL-6 peaked at 2 and 6 hours in a time-dependent manner, respectively. CONCLUSION: In conclusion, the production of proinflammatory cytokine might be mediated by the binding of sPLA2-IIA to the receptors.

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