- Neglected extensive Aspergillus osteomyelitis of the pelvis, femur, and vertebra in an immunocompetent patient: a case report
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Roop Singh, Anas Delair, Svareen Kaur, Monika Gupta
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Received February 19, 2023 Accepted April 23, 2023 Published online May 15, 2023
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DOI: https://doi.org/10.12701/jyms.2023.00185
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 Abstract
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- De novo Aspergillus infections of the appendicular skeleton are rare. A 72-year-old female presented with pain and deformity of the left lower limb and an inability to bear weight that had persisted for the last 6 months. A biopsy of the femur confirmed the diagnosis of extensive Aspergillus osteomyelitis, and the patient was treated with amphotericin B and oral voriconazole. The patient died of coronavirus disease 2019 after 2.5 months of treatment. A diagnosis of Aspergillus osteomyelitis may be delayed because of its varied clinical presentation. To the best of our knowledge, this is the first known case of de novo neglected and extensive (multisite, multibone) Aspergillus osteomyelitis in an immunocompetent patient. This case highlights the importance of awareness in patients and treating physicians of this rare infection and its early diagnosis to prevent extensive spread.
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E-Submission
Yeungnam University College of Medicine
