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JYMS : Journal of Yeungnam Medical Science

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Seung Kyu Kim 2 Articles
A Case of ANCA-Negative Generalized Wegener's Granulomatosis.
Seung Kyu Kim, Yong Jin Kwon, Heae Surng Park, Kwang Won Rhee, Ji Yoon Ha, Hee Sung Ko, Ki Hyun Kim, Min Kwang Byun
Yeungnam Univ J Med. 2013;30(1):17-20.   Published online June 30, 2013
DOI: https://doi.org/10.12701/yujm.2013.30.1.17
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AbstractAbstract PDF
Wegener's granulomatosis is a very rare systemic vasculitis characterized by necrotizing granulomatosis. The detection of antineutrophil cytoplasm antibody (ANCA) is a valuable finding in diagnosing Wegener's granulomatosis because ANCA is positive in approximately 90 percent of patients with active, generalized Wegener's granulomatosis. But ANCA is not necessarily positive to make a diagnosis. A 59-year-old man was transferred to our hospital. He was diagnosed with lung abscess and treated with antibiotics at previous hospital. Initially, the ANCA was negative in immunofluorescence assay but we suspected Wegener's granulomatosis because of systemic inflammatory symptoms. Clinical symptoms deteriorated rapidly so we did bronchoscopic biopsy early. Wegener's granulomatosis was diagnosed according to pathologic finding that reported necrotizing granulomatous inflammation associated with vasculitis. Thus we treated with steroid then clinical symptoms and laboratory findings were improved.
A Case of Adrenocortical Carcinoma Secreting Cortisol and Aldosterone.
Jiyoon Ha, Min Kyung Kim, Yoon Jin Cha, Seung Kyu Kim, Gi Young Yun, Kwangwon Rhee, Joon Seong Park, Eun Suk Cho, Chul Woo Ahn, Jong Suk Park
Yeungnam Univ J Med. 2012;29(2):132-135.   Published online December 31, 2012
DOI: https://doi.org/10.12701/yujm.2012.29.2.132
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AbstractAbstract PDF
Adrenocortical carcinomas are rare and frequently aggressive tumors that may be functional (hormone-secreting) and may cause Cushing's syndrome or virilization, or non-functional and manifest as an abdominal mass. This paper reports the case of a 77-year-old woman with cortisol- and aldosterone-secreting adrenal carcinoma. The patient complained of general weakness, a moon face, and weight gain. She also had hypokalemia and hypertension. Her endocrinological data showed excessive aldosterone production and non-suppressible cortisol production in a low-dose dexamethasone suppresion test. Her abdominal CT showed a right adrenal mass. She underwent right adrenalectomy, and her histology revealed the presence of adrenocortical carcinoma. After adrenalectomy, her hypokalemia returned to normal and she is being treated with hydrocortisone.

JYMS : Journal of Yeungnam Medical Science
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