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JYMS : Journal of Yeungnam Medical Science

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Yoojin Lindsey Chung 1 Article
Effective and appropriate use of weight loss medication in pediatric obesity: a narrative review
Yoojin Lindsey Chung
J Yeungnam Med Sci. 2024;41(3):158-165.   Published online July 2, 2024
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AbstractAbstract PDF
Over the past few decades, there has been a notable increase in the incidence of pediatric obesity, which is a significant public health concern. Children who are obese have a greater risk of type 2 diabetes, hypertension, dyslipidemia, polycystic ovary syndrome, obstructive sleep apnea, and adult obesity. Lifestyle modification therapy is typically the initial approach to treat pediatric obesity. For patients who do not achieve success with lifestyle modification therapy alone, pharmacotherapy is the next logical treatment option. When selecting an anti-obesity medication (AOM), it is essential to first ascertain the medical background of the patient, including current medications and obesity-associated comorbidities. Evaluation of obesity phenotypes in patients may also be beneficial. AOMs for pediatric obesity include metformin, orlistat, glucagon-like peptide 1 agonists, phentermine, and the phentermine/topiramate combination. Sufficient lifestyle modification therapy should be administered before considering pharmacotherapy and continued after the initiation of AOM. To ensure healthy development, monitoring growth and puberty development during anti-obesity treatments is essential.


Citations to this article as recorded by  
  • Exploring comprehensive insights into pediatric obesity
    Yong Hee Hong
    Journal of Yeungnam Medical Science.2024; 41(3): 139.     CrossRef

JYMS : Journal of Yeungnam Medical Science