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JYMS : Journal of Yeungnam Medical Science

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Resident fellow section: Clinical vignette
Cephalosporin-induced encephalopathy in patients with hematologic malignancies: a significant concern
Young Seob Park, Min Kyoung Kim, Kyung Hee Lee, Sung Ae Koh, Ji Yoon Jung, Byeong Il Jang, Se-Jin Lee
J Yeungnam Med Sci. 2023;40(Suppl):S137-S141.   Published online November 14, 2023
DOI: https://doi.org/10.12701/jyms.2023.00864
  • 1,126 View
  • 40 Download
PDF
Case reports
Negative myoclonus associated with tramadol use
Seong Yoon Bae, Se-Jin Lee
Yeungnam Univ J Med. 2020;37(4):329-331.   Published online April 23, 2020
DOI: https://doi.org/10.12701/yujm.2020.00108
  • 7,458 View
  • 181 Download
  • 1 Crossref
AbstractAbstract PDF
Negative myoclonus (NM) is a shock-like jerky involuntary movement caused by a sudden, brief interruption of tonic muscle contraction. NM is observed in patients diagnosed with epilepsy, metabolic encephalopathy, and drug toxicity and in patients with brain lesions. A 55-year-old man presented with NM in both his arms and neck. He has taken medications containing tramadol at a dose of 80–140 mg/day for 5 days due to common cold. He had no history of seizures. Acute lesions were not observed during magnetic resonance imaging, and abnormal findings in his laboratory tests were not noted. His NM resolved completely after the discontinuation of tramadol and the oral administration of clonazepam. Our case report suggests that tramadol can cause NM in patients without seizure history or metabolic disorders, even within its therapeutic dose.

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Citations to this article as recorded by  
  • Tramadol Induced Jerks
    Waiz Wasey, Imad Aziz, Sharefi Saleh, Naila Manahil, Neha Wasey
    Cureus.2021;[Epub]     CrossRef
Isolated hemorrhage in the cerebellar vermis with vertigo and body lateropulsion to the contralesional side
Dong Hyun Lee, Se-Jin Lee
Yeungnam Univ J Med. 2019;36(3):269-272.   Published online September 9, 2019
DOI: https://doi.org/10.12701/yujm.2019.00318
  • 6,315 View
  • 95 Download
AbstractAbstract PDF
There have been several reports of patients with isolated lesions of the cerebellar vermis presenting with clinical features similar to those of peripheral vestibulopathy. We report a case of small, isolated hematoma in the cerebellar vermis in a patient who presented with vertigo, ipsilesional nystagmus, and body lateropulsion to the contralesional side without the usual signs or symptoms of cerebellar dysfunction. Although they present with symptoms that mimic those of peripheral vestibulopathy, and brain computed tomography shows no abnormality, as there may be a small, isolated hematoma or infarction in the cerebellar vermis. Thus, brain magnetic resonance imaging should be performed in elderly patients with vascular risk factors.
Case Report
Negative myoclonus associated with pregabalin
Kwan-Do Park, Min-Ku Kim, Se-Jin Lee
Yeungnam Univ J Med. 2018;35(2):240-243.   Published online December 31, 2018
DOI: https://doi.org/10.12701/yujm.2018.35.2.240
  • 6,452 View
  • 88 Download
  • 4 Crossref
AbstractAbstract PDF
Negative myoclonus (NM) is a jerky, shock-like involuntary movement caused by a sudden, brief interruption of muscle contraction. An 80-year-old man presented with multifocal NM and confusion. Two days before the onset of NM, he commenced the intake of pregabalin at a dose of 150 mg/day for neuropathic pain. His NM resolved completely and mental status improved gradually after the administration of lorazepam intravenously and the discontinuation of pregabalin. Our study suggests that pregabalin can cause NM even in patients without a history of seizures.

Citations

Citations to this article as recorded by  
  • Movement disorders associated with antiseizure medications: A systematic review
    Daniel J. Zhou, Spriha Pavuluri, Isha Snehal, Cynthia M. Schmidt, Miguel Situ-Kcomt, Olga Taraschenko
    Epilepsy & Behavior.2022; 131: 108693.     CrossRef
  • Electrophysiological characteristics and anatomical differentiation of epileptic and non-epileptic myoclonus
    Mohammad Abu-Hegazy, Azza Elmoungi, Eman Eltantawi, Ahmed Esmael
    The Egyptian Journal of Neurology, Psychiatry and Neurosurgery.2021;[Epub]     CrossRef
  • Pregabalin-associated movement disorders: A literature review
    JamirPitton Rissardo, AnaLetícia Fornari Caprara
    Brain Circulation.2020; 6(2): 96.     CrossRef
  • Negative myoclonus associated with tramadol use
    Seong Yoon Bae, Se-Jin Lee
    Yeungnam University Journal of Medicine.2020; 37(4): 329.     CrossRef

JYMS : Journal of Yeungnam Medical Science
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