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Review article
- Endocrinology, Diabetes, and Metabolism
- Screening and treatment of endocrine hypertension focusing on adrenal gland disorders: a narrative review
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Seung Min Chung
- J Yeungnam Med Sci. 2024;41(4):269-278. Published online September 19, 2024
- DOI: https://doi.org/10.12701/jyms.2024.00752
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- 2 Web of Science
- 3 Crossref
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Abstract
PDF - Most cases of high blood pressure have no identifiable cause, termed essential hypertension; however, in approximately 15% of cases, hypertension occurs due to secondary causes. Primary aldosteronism (PA) and pheochromocytoma and paraganglioma (PPGL) are representative endocrine hypertensive diseases. The differentiation of endocrine hypertension provides an opportunity to cure and prevent target organ damage. PA is the most common cause of secondary hypertension, which significantly increases the risk of cardiovascular disease compared to essential hypertension; thus, patients with clinical manifestations suggestive of secondary hypertension should be screened for PA. PPGL are rare but can be fatal when misdiagnosed. PPGL are the most common hereditary endocrine tumors; therefore, genetic testing using next-generation sequencing panels is recommended. Herein, we aimed to summarize the characteristic clinical symptoms of PA and PPGL and when and how diagnostic tests and treatment strategies should be performed.
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Citations
Citations to this article as recorded by
- Mechanisms linking hypertension to cardiovascular and cerebrovascular diseases and their clinical implications: A comprehensive review
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Clinical and Experimental Hypertension.2026;[Epub] CrossRef - Clinical course and management of adrenal endocrine hypertension: A single-center experience
Ines Bayar, Hanene Sayadi, Farah Ayachi, Bilel Ben Amor, Sana Abid, Ekram Hajji, Hela Marmouch, Ines Khochtali
Endocrine Regulations.2026; 60(1): 221. CrossRef - PHEOCHROMOCYTOMA AND PARAGANGLIOMA: CLINICAL PICTURE, DIAGNOSIS, TREATMENT, FOLLOW-UP AND PROGNOSIS - A LITERATURE REVIEW
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International Journal of Innovative Technologies in Social Science.2025;[Epub] CrossRef
- Mechanisms linking hypertension to cardiovascular and cerebrovascular diseases and their clinical implications: A comprehensive review
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