Lymphangioleiomyomatosis (LAM) is a rare, cystic lung disease that is associated with mutation in the tuberous sclerosis genes, renal angiomyolipomas, lymphatic spread and a remarkable female gender predilection. The pathology of LAM is represented by the proliferation of immature smooth muscle cells in the walls of airways, and venules and lymphatic vessels in the lung. The clinical course of LAM is characterized by progressive dyspnea on exertion, recurrent pneumothorax and collections of chylous fluid. The diagnosis of pulmonary LAM can be made on chest X-ray, a high-resolution CT scan and lung biopsy. We experienced a case of pulmonary lymphangioleiomyomatosis in a 28-years-old female patient who had suffered from progressive dyspnea on exertion, so we report on it along with a brief review of the relevant literature.
Angioleiomyoma of the sinonasal tract is a rare benign tumor. We report a case of angioleiomyoma of the nasal septum in a 51-year-old woman who complained of frequent epistaxis for 3 months. Surgicalexcision was performed. The excised specimen was 0.7 x 0.5 x 0.4 cm in size, well circumscribed, grayish white, rubbery, and soft. Histological examination showed thick-walled blood vessels and smooth muscle cell proliferation. No nuclear atypia or mitoses were present.
Citations
Citations to this article as recorded by
A Case of Leiomyoma of the Nasal Septum Sung Jae Heo, Jin Hyun Ryu, Jung Soo Kim Journal of Clinical Otolaryngology Head and Neck Surgery.2016; 27(1): 133. CrossRef
A Case of Vascular Leiomyoma in Nasal Cavity: Case Report and Literature Review Sung Won Yoon, Min Joon Park, Eun Mee Han, Jung Hyeob Sohn Korean Journal of Otorhinolaryngology-Head and Neck Surgery.2015; 58(2): 138. CrossRef
A Case of Angioleiomyoma of the Nasal Septum Won Il Park, Ji Sung Shim, Junbum Joo, Ju Eun Cho Journal of Clinical Otolaryngology Head and Neck Surgery.2013; 24(2): 247. CrossRef