BACKGROUND Clinical differences in Mycoplasma pneumonia (MP) in children and adolescent patients according to abnormal infiltrate patterns on the chest X-ray were compared. METHODS: From 2012 to 2015, patients (n=336) diagnosed with MP at Yeungnam University Medical Center have been classified as eiher lobar pneumonia or bronchopneumonia based on the infilterate patterns observed on chest X-ray. Cases were analyzed retrospectively for gender, age, seasonal incidence rate, main symptoms (fever duration, extrapulmonary symptoms), and laboratory results, including white blood cell count, hemoglobin, platelets, C-reactive protein (CRP), and erythrocyte sedimentation rate (ESR), as well as concurrent respiratory virus infection. RESULTS: The following results were observed. First, lobar pneumonia affected 22.0% of all MP patients and was the most common in preschool children, with a high incidence rate in November and December. Second, lobar pneumonia had a longer fever duration than bronchopneumonia (p<0.001), and also showed significantly higher platelets (336.8 vs. 299.1 k/µL, p=0.026), ESR(46.3 vs. 26.0mm/hr, p<0.001) and CRP (4.86 vs. 2.18mg/dL, p=0.001). Third, viral co-infection was more common in bronchopneumonia (p=0.017), affecting 66.7% of infants and toddlers (p=0.034). Finaly, lobar consolidation was most common in both lower lobes. CONCLUSION: MP in children has increased in younger age groups, and the rate of lobar pneumonia with severe clinical symptoms is higher in older children.
BACKGROUND The incidence of acute hepatitis A in adults has recently been increasing. This study was conducted to investigate the epidemiology and clinical characteristics of acute hepatitis A in Daegu province over the past 10 years. MATERIALS AND METHODS: We reviewed the medical records of 55 patients (male/female: 34/21), who were diagnosed with acute hepatitis A by confirmation of the IgM anti-HAV between January 1998 and June 2007. RESULTS: The mean age was 29.7+/-10.3 years (range; 17-65 years). The incidence was most common between March and June (56.1%), in the third and fourth decades of life (78.2%) and 90.9% (50/55) of the patients were diagnosed from 2003 to present. The common symptoms included anorexia, nausea or vomiting (69.1%), fever and chills (49.1%), myalgia (47.3%), weight loss (47.3%), fatigue (40.0%), abdominal pain (36.4%), diarrhea (9.1%) and pruritus (5.5%). The mean duration of hospital stay was 8.6+/-3.4 days (range; 3-20 days). The route of transmission was identified in only 11 patients (20.0%); 7 patients (12.7%) traveled (abroad or domestic), 2 patients (3.6%) ingested raw food and 2 patients (3.6%) had friends with acute hepatitis A. Fifty four patients recovered without complication; one patient developed fulminant hepatitis and recovered after a liver transplantation. CONCLUSION: The incidence of acute hepatitis A in adults is increasing. Because of the cost of treatment and potential for serious disease, persons, under 40 are recommened to have hepatitis A vaccination and confirmation of IgG anti-HAV.
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Pattern of Hepatitis A Incidence According to Area Characteristics Using National Health Insurance Data Joo Youn Seo, Jae Hee Seo, Myoung Hee Kim, Moran Ki, Hee Suk Park, Bo Youl Choi Journal of Preventive Medicine & Public Health.2012; 45(3): 164. CrossRef
Pediatric bipolar disorder(BD) is one of the significant psychiatric health problems, which begins in childhood, has chronic persisting clinical course and leads impairs academic, occupational and legal problems of the patients. Fortunately, there has been increasing recognition of pediatric bipolar disorder during the past 10 years, even there are still controversy about clinical features and diagnosis. The clinical presentation of pediatric BD is greatly different to classic BD, relatively higher percentage of mixed, rapid cycling subtypes, not episodic and chronic lasting nature. In addition, pediatric BD has many comorbid psychiatric conditions such as attention deficit hyperactivity disorder, anxiety disorder and that makes more difficult to treat the patients with pediatric BD. To reduce confusion about diagnosis, the National Institute of Mental Health Research Roundtable divided pediatric BD into narrow and broad phenotype. 1) Given the paucity of medication trial studies of pediatric BD, no psychotrophic medications have been approved by U.S. Food and Drug Administration, except lithium. There have been a few open trials and retrospective chart reviews on the efficacy and side effects of mood stabilizers, anticonvulsants and atypical antipsychotics. More short and long-term randomized, double blind, well controlled trials of medication for pediatric BD are needed.