Journal of Yeungnam Medical Science

Original Article

Significance of the AFP Level and HBsAg in Differentiation of Hepatic Masses.: Jae Woon Kim, Won Kyu Park, Jae Ho Cho, Jae Chun Chang, Bok Hwan Park; Yeungnam Univ J Med. 1996;13(2):302-307. Published online December 31, 1996; DOI: https://doi.org/10.12701/yujm.1996.13.2.302

Abstract PDF: Hepatic masses show different enhancing patterns in N bolus computed tomography: Hepatocellular carcinoma shows high-attenuation in the early enhancing phase and low-attenuation in the late enhancing phase, hemangioma shows peripheral dot-like high-attenuation in the early enhancing phase and central high-attenuation in the late enhancing phase, and metastatic cancer and cholangiocelluar carcinoma show peripheral high-attenuation rim in the early enhancing phase and central portion gradulally high attenuation in the late enhancing phase. but sometimes enhancing patterns of the hepatic masses are confuse. To evaluate the significance of the AFP level and HBsAg in differentiation of the hepatic masses, we retrospectively analyzed AFP level and HBsAg' in 228 pathologically or radiologically confirmed hepatocellular carcinomas, and 137 pathologically nonhepatocellular cacinomas. The results were as follows In hepatocellular carcinoma, AFP level above 20ng/ml was 77.8% and HBsAg positve was 72.6%. In nonhepatocellular carcinoma, AFP level above 20ng/ml was 3.7% and HBsAg positve was 16.1%. We concluded that AFP level and HBsAg are helpful to distinguish hepatocellular carcinoma from nonhepatocellular carcinoma, when IV bolus computed tomogram finding is uncertain.

Case Report

A Case of Hepatocellular Carcinoma after Hepatic Artery Ligation.: Jeong Ill Suh, Joon Hwan Kim, Dong Joon Lee, Ki Yoon Kim, Ho Jung Kang, Chan Won Park, Heon Ju Lee; Yeungnam Univ J Med. 1996;13(1):146-151. Published online June 30, 1996; DOI: https://doi.org/10.12701/yujm.1996.13.1.146

Abstract PDF: Majority of .hepatocellular carcinoma is evolved from a well differentiated cancerous condition such as hypetptastic lesions eg; adenomatous hyperplasia in cirrhotic liver or de no vo carcinogenesis and prolifenation along with dedifferentiation. Adenomatous hyperplasia is may be seen in severe acute hepatic injury, like svhmassive hepatic necrosis, or in chronic liver diseases, particularly liver cirrhosis and it has recently attracted much interest from both clinicians and pathologists because it is regarded as a precursor lesion of hepatocObdar carcinoma. Hepatic. denomatous hyperplasia resembling focal nodular hyperplasia might have developed from localized vascular changes associated with chronic liver disease, pre-existing arterial malformation and early stage of angiogenesis in hepatocarcinogenesis. .fie present a patient who developed hepatocellular carcinoma after hepatic artery ligation.

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