Journal of Yeungnam Medical Science

Review articles

Understanding insomnia as systemic disease: Seokho Yun, Sohye Jo; Yeungnam Univ J Med. 2021;38(4):267-274. Published online September 13, 2021; DOI: https://doi.org/10.12701/yujm.2021.01424

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Sleep plays a critical role in homeostasis of the body and mind. Insomnia is a disease that causes disturbances in the initiation and maintenance of sleep. Insomnia is known to affect not only the sleep process itself but also an individual’s cognitive function and emotional regulation during the daytime. It increases the risk of various neuropsychiatric diseases such as depression, anxiety disorder, and dementia. Although it might appear that insomnia only affects the nervous system, it is also a systemic disease that affects several aspects of the body, such as the cardiovascular, endocrine, and immune systems; therefore, it increases the risk of various diseases such as hypertension, diabetes mellitus, and infection. Insomnia has a wide range of effects on our bodies because sleep is a complex and active process. However, a high proportion of patients with insomnia do not seek treatment, which results in high direct and indirect costs. This is attributed to the disregard of many of the negative effects of insomnia. Therefore, we expect that understanding insomnia as a systemic disease will provide an opportunity to understand the condition better and help prevent secondary impairment due to insomnia.

Citations

Citations to this article as recorded by

Medical service utilization patterns among adults with insomnia: A retrospective cohort study
Min Kyung Hyun, Jang Won Lee
European Journal of Integrative Medicine.2024; 67: 102325. CrossRef
Socio-Ecological Context of Sleep: Gender Differences and Couples’ Relationships as Exemplars
Andrea N. Decker, Alexandra R. Fischer, Heather E. Gunn
Current Psychiatry Reports.2022; 24(12): 831. CrossRef
Clinical Spectrum and Trajectory of Innovative Therapeutic Interventions for Insomnia: A Perspective
Yun-Jo Lo, Viraj Krishna Mishra, Hung-Yao Lo, Navneet Kumar Dubey, Wen-Cheng Lo
Aging and disease.2022;[Epub] CrossRef
Understanding sleep and sleep disturbances in autism spectrum disorder, and management of insomnia: an update
Hye-Geum Kim
Yeungnam University Journal of Medicine.2021; 38(4): 265. CrossRef

An update on the cause and treatment of sleep disturbance in children and adolescents with autism spectrum disorder: Wan Seok Seo; Yeungnam Univ J Med. 2021;38(4):275-281. Published online September 13, 2021; DOI: https://doi.org/10.12701/yujm.2021.01410

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Abstract PDF

Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by abnormalities in social communication/interaction and restrictive, repetitive patterns of behavior. ASD is a relatively common psychiatric disorder, with a prevalence of approximately 1.7% in children. Although many children and adolescents with ASD visit the hospital for medical help for emotional and behavioral problems such as mood instability and self-harming behavior, there are also many visits for sleep disturbances such as insomnia and sleep resistance. Sleep disturbances are likely to increase fatigue and daytime sleepiness, impaired concentration, negatively impact on daytime functioning, and pose challenges in controlling anger and aggressive behavior. Sleep disturbance in children and adolescents with ASD negatively affects the quality of life, nothing to say the quality of life of their families and school members. In this review, sleep disturbances that are common in children and adolescents with ASD and adolescents are presented. The developmental and behavioral impacts of sleep disturbances in ASD were also considered. Finally, non-pharmacological and pharmacological treatments for sleep disturbances in children and adolescents with ASD and adolescents are reviewed.

Citations

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Current Pharmacological Treatment for Sleep Disorders in Children and Adolescents with Autism Spectrum Disorder
Hatice Altun, Semiha Cömertoğlu Arslan
European Journal of Therapeutics.2024;[Epub] CrossRef
Sleep and Autism Spectrum Disorder: A Comprehensive Review of Diagnosis, Markers, Interventions, and Treatments
Deepa Burman, Karthikeyan Ramanujam, Dilshad Manzar, Vijay Kumar Chattu, David Warren Spence, Nevin F. W. Zaki, Haitham Jahrami, Seithikurippu R. Pandi-Perumal
Sleep and Vigilance.2023; 7(1): 9. CrossRef
Efficacy of Melatonin for Insomnia in Children with Autism Spectrum Disorder: A Meta-analysis
Mei Xiong, Fang Li, Zhaohua Liu, Xin Xie, Hongli Shen, Weiteng Li, Liping Wei, Rongfang He
Neuropediatrics.2023; 54(03): 167. CrossRef
Sleep disturbances and emotional dysregulation in young children with autism spectrum, intellectual disability, or global developmental delay
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Sleep Medicine.2023; 105: 45. CrossRef
Where I am from matters: factors influencing behavioral and emotional changes in autistic individuals during COVID-19 in Latin America
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Frontiers in Psychiatry.2023;[Epub] CrossRef
A novel case of prolonged Ifosfamide encephalopathy and long-term treatment with methylene blue: a case report and review of literature
Gabriel Chain, Mudit Kalia, Karen Kestenbaum, Lara Pappas, Anna Sechser-Perl, Gadi Abebe Campino, Nibal Zaghloul
BMC Pediatrics.2022;[Epub] CrossRef
Sleep Disturbances in Children Affected by Autism Spectrum Disorder
Jessica Galli, Erika Loi, Lucrezia Maria Visconti, Paola Mattei, Anna Eusebi, Stefano Calza, Elisa Fazzi
Frontiers in Psychiatry.2022;[Epub] CrossRef
Analysis of sleep problem in children aged 1–3 years with autism spectrum disorder in Zhejiang province, China
Dan Yao, Shasha Wang, Fangfang Li, Minjie Gao, Jie Shao
Frontiers in Psychiatry.2022;[Epub] CrossRef
Understanding sleep and sleep disturbances in autism spectrum disorder, and management of insomnia: an update
Hye-Geum Kim
Yeungnam University Journal of Medicine.2021; 38(4): 265. CrossRef

Effects and mechanisms of a mindfulness-based intervention on insomnia: Hye-Geum Kim; Yeungnam Univ J Med. 2021;38(4):282-288. Published online January 14, 2021; DOI: https://doi.org/10.12701/yujm.2020.00850

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Abstract PDF

Medication alone is not sufficient to treat insomnia. In addition, the side effects of sleep medications themselves cannot be ignored during treatment. Insomnia begins with poor sleep quality and discomfort, but as it continues, patients fall into a vicious circle of insomnia with negative thoughts and dysfunctional and distorted perceptions related to sleep. Mindfulness-based intervention for insomnia corrects these sequential cognitive and behavioral processes. The mindfulness technique basically recognizes all the thoughts, feelings, and experiences that occur to us as they are, nonjudgmentally, and then trains them to return to the senses of our body. In this way, while noticing all the processes of the sequential vicious cycle and training them to return to our bodies (e.g., breathing), mindfulness determines whether we are really sleepy or just fatigued. This mindfulness-based intervention can be a useful nonpharmaceutical intervention for insomnia, and its stability and efficacy has been proven by many studies.

Citations

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Comparative efficacy and acceptability of interventions for insomnia in breast cancer patients: A protocol for systematic review and network meta-analysis
Zhifan Li, Qian Wang, Junxia Xu, Qihua Song, Xiaoling Ling, Ya Gao, Junqiang Lei, Andrea Giannini
PLOS ONE.2023; 18(3): e0282614. CrossRef
Cognitive and Somatic Mediators of the Effects of Trait Mindfulness on Mental Health Adjustment Following Bereavement
Mariel Emrich, Crystal L. Park, Adam B. David, Lucy Finkelstein-Fox
Mindfulness.2023; 14(12): 2932. CrossRef
Effectiveness of a 4-Day Mindfulness-Based Intervention in a 2-Month Follow-Up for Chinese Incarcerated People
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Behavior Therapy.2022; 53(5): 981. CrossRef
Understanding sleep and sleep disturbances in autism spectrum disorder, and management of insomnia: an update
Hye-Geum Kim
Yeungnam University Journal of Medicine.2021; 38(4): 265. CrossRef
Effects of mindful breathing combined with sleep-inducing exercises in patients with insomnia
Hui Su, Li Xiao, Yue Ren, Hui Xie, Xiang-Hong Sun
World Journal of Clinical Cases.2021; 9(29): 8740. CrossRef

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