Journal of Yeungnam Medical Science

Review articles

Hepatic ischemia-reperfusion injury with respect to oxidative stress and inflammatory response: a narrative review: Eun Kyung Choi, Dong Gun Lim; J Yeungnam Med Sci. 2023;40(2):115-122. Published online March 21, 2022; DOI: https://doi.org/10.12701/jyms.2022.00017

4,270 View
149 Download
14 Web of Science
15 Crossref

Hepatic ischemia-reperfusion injury is a major complication of liver transplantation, trauma, and shock. This pathological condition can lead to graft dysfunction and rejection in the field of liver transplantation and clinical hepatic dysfunction with increased mortality. Although the pathological mechanisms of hepatic ischemia-reperfusion injury are very complex, and several intermediators and cells are involved in this phenomenon, oxidative stress and inflammatory responses are the key processes that aggravate hepatic injury. This review summarizes the current understanding of oxidative stress and inflammatory responses and, in that respect, addresses the therapeutic approaches to attenuate hepatic ischemia-reperfusion injury.

Citations

Citations to this article as recorded by

Thymoquinone-loaded self-nano-emulsifying drug delivery system against ischemia/reperfusion injury
Badr Bahloul, Roua Chaabani, Yosri Zahra, Nesrine Kalboussi, Jamil Kraiem, Souad Sfar, Nathalie Mignet, Hassen ben Abdennebi
Drug Delivery and Translational Research.2024; 14(1): 223. CrossRef
Modafinil lightens apoptosis and inflammatory response in hepatic ischemia‐reperfusion injury through inactivation of TLR9/Myd88/p38 signaling
Tairan Zhang, Xidong Wang
Drug Development Research.2024;[Epub] CrossRef
Cellular and molecular mechanisms of hepatic ischemia-reperfusion injury: The role of oxidative stress and therapeutic approaches
Joseph George, Yongke Lu, Mutsumi Tsuchishima, Mikihiro Tsutsumi
Redox Biology.2024; 75: 103258. CrossRef
Recent advances in fluorescent probes for ATP imaging
Chen Zhang, Guanzhao Wu
Talanta.2024; 279: 126622. CrossRef
Protective effect of irbesartan against hepatic ischemia–reperfusion injury in rats: role of ERK, STAT3, and PPAR-γ inflammatory pathways in rats
Salma A. El-Marasy, Rasha E. Mostafa, Hoda B. Mabrok, Marwa S. Khattab, Sally A. El Awdan
Naunyn-Schmiedeberg's Archives of Pharmacology.2024;[Epub] CrossRef
Reversible Fluorescent Probes for Dynamic Imaging of Liver Ischemia-Reperfusion Injury
Wen Zhang, Jihong Liu, Ping Li, Xin Wang, Bo Tang
Accounts of Chemical Research.2024; 57(17): 2594. CrossRef
Flavonoids as therapeutics for myocardial ischemia-reperfusion injury: a comprehensive review on preclinical studies
Vipin Kumar Verma, Priya Bhardwaj, Vaishali Prajapati, Avantika Bhatia, Sayani Purkait, Dharamvir Singh Arya
Laboratory Animal Research.2024;[Epub] CrossRef
ZLN005, a PGC-1α Activator, Protects the Liver against Ischemia–Reperfusion Injury and the Progression of Hepatic Metastases
Celine Tohme, Tony Haykal, Ruiqi Yang, Taylor J. Austin, Patricia Loughran, David A. Geller, Richard L. Simmons, Samer Tohme, Hamza O. Yazdani
Cells.2024; 13(17): 1448. CrossRef
Treatment of Acute and Long-COVID, Diabetes, Myocardial Infarction, and Alzheimer’s Disease: The Potential Role of a Novel Nano-Compound—The Transdermal Glutathione–Cyclodextrin Complex
Ray Yutani, Vishwanath Venketaraman, Nisar Sheren
Antioxidants.2024; 13(9): 1106. CrossRef
Fluorescent probes for sensing peroxynitrite: biological applications
Yan Yang, Jinting Shang, Yiyuan Xia, Yuran Gui
Redox Report.2024;[Epub] CrossRef
An update on the molecular mechanism and pharmacological interventions for Ischemia-reperfusion injury by regulating AMPK/mTOR signaling pathway in autophagy
Bin Tang, Zhijian Luo, Rong Zhang, Dongmei Zhang, Guojun Nie, Mingxing Li, Yan Dai
Cellular Signalling.2023; : 110665. CrossRef
Unveiling the Crucial Roles of O2•–and ATP in Hepatic Ischemia–Reperfusion Injury Using Dual-Color/Reversible Fluorescence Imaging
Jihong Liu, Wen Zhang, Xin Wang, Qi Ding, Chuanchen Wu, Wei Zhang, Luling Wu, Tony D. James, Ping Li, Bo Tang
Journal of the American Chemical Society.2023; 145(36): 19662. CrossRef
New insights into ischemia-reperfusion injury signaling pathways in organ transplantation
Kenneth J. Dery, Jerzy W. Kupiec-Weglinski
Current Opinion in Organ Transplantation.2022; 27(5): 424. CrossRef
Isolongifolene alleviates liver ischemia/reperfusion injury by regulating AMPK-PGC1α signaling pathway-mediated inflammation, apoptosis, and oxidative stress
Jinjin Li, Jie Li, Hongbo Fang, Hang Yang, Tianchun Wu, Xiaoyi Shi, Chun Pang
International Immunopharmacology.2022; 113: 109185. CrossRef
Molecularly Designed Ion-Imprinted Nanoparticles for Real-Time Sensing of Cu(II) Ions Using Quartz Crystal Microbalance
Nihan Aydoğan, Gülgün Aylaz, Monireh Bakhshpour, Tugba Tugsuz, Müge Andaç
Biomimetics.2022; 7(4): 191. CrossRef

Can antioxidants be effective therapeutics for type 2 diabetes?: Soyoung Park, So-Young Park; Yeungnam Univ J Med. 2021;38(2):83-94. Published online October 8, 2020; DOI: https://doi.org/10.12701/yujm.2020.00563

11,314 View
228 Download
16 Crossref

Abstract PDF

The global obesity epidemic and the growing elderly population largely contribute to the increasing incidence of type 2 diabetes. Insulin resistance acts as a critical link between the present obesity pandemic and type 2 diabetes. Naturally occurring reactive oxygen species (ROS) regulate intracellular signaling and are kept in balance by the antioxidant system. However, the imbalance between ROS production and antioxidant capacity causes ROS accumulation and induces oxidative stress. Oxidative stress interrupts insulin-mediated intracellular signaling pathways, as supported by studies involving genetic modification of antioxidant enzymes in experimental rodents. In addition, a close association between oxidative stress and insulin resistance has been reported in numerous human studies. However, the controversial results with the use of antioxidants in type 2 diabetes raise the question of whether oxidative stress plays a critical role in insulin resistance. In this review article, we discuss the relevance of oxidative stress to insulin resistance based on genetically modified animal models and human trials.

Citations

Citations to this article as recorded by

Effect of substitution of wheat flour with chickpea flour on their physico-chemical characteristics
Jiwan S. Sidhu, Tasleem Zafar, Abdulwahab Almusallam, Muslim Ali, Amani Al-Othman
Arab Gulf Journal of Scientific Research.2024; 42(2): 290. CrossRef
Mulberry polyphenols restored both small and large intestinal microflora indb/dbmice, potentially alleviating type 2 diabetes
Fuhua Li, Jian Ming
Food & Function.2024; 15(16): 8521. CrossRef
Effects of Purified Vitexin and Iso-Vitexin from Mung Bean Seed Coat on Antihyperglycemic Activity and Gut Microbiota in Overweight Individuals’ Modulation
Pornlada Yutharaksanukul, Preuk Tangpromphan, Paiboon Tunsagool, Sudathip Sae-tan, Sunee Nitisinprasert, Surasawadee Somnuk, Massalin Nakphaichit, Nut Pusuntisumpun, Bandhita Wanikorn
Nutrients.2024; 16(17): 3017. CrossRef
The positive implication of natural antioxidants on oxidative stress-mediated diabetes mellitus complications
Shouvik Mallik, Bijoy Paria, Sayed Mohammad Firdous, Hesham S. Ghazzawy, Nashi K. Alqahtani, Yong He, Xiaoli Li, Mostafa M. Gouda
Journal of Genetic Engineering and Biotechnology.2024; 22(4): 100424. CrossRef
Maternal dietary antioxidant supplementation regulates weaned piglets’ adipose tissue transcriptome and morphology
Hernán D. Laviano, Gerardo Gómez, Yolanda Núñez, Juan M. García-Casco, Rita M. Benítez, Ana de las Heras-Molina, Fernando Gómez, Fernando Sánchez-Esquiliche, Beatriz Martínez-Fernández, Antonio González-Bulnes, Ana I. Rey, Clemente J. López-Bote, María Mu
PLOS ONE.2024; 19(9): e0310399. CrossRef
Oxidised phosphatidylcholine induces sarcolemmal ceramide accumulation and insulin resistance in skeletal muscle
Karin A. Zemski Berry, Amanda Garfield, Purevsuren Jambal, Simona Zarini, Leigh Perreault, Bryan C. Bergman
Diabetologia.2024; 67(12): 2819. CrossRef
Mitochondrial Dysfunction as a Factor of Energy Metabolism Disorders in Type 2 Diabetes Mellitus
Alexander Blagov, Ludmila Nedosugova, Tatiana Kirichenko, Vasily Sukhorukov, Alexandra Melnichenko, Alexander Orekhov
Frontiers in Bioscience-Scholar.2024;[Epub] CrossRef
The consumption of date palm fruits as a source of bioactive compounds in patients with type 2 diabetes: a cross sectional study
M.Q. Al-Mssallem
Acta Horticulturae.2023; (1371): 381. CrossRef
Aging, oxidative stress and degenerative diseases: mechanisms, complications and emerging therapeutic strategies
Mani Raj Chaudhary, Sakshi Chaudhary, Yogita Sharma, Thokchom Arjun Singh, Alok Kumar Mishra, Shweta Sharma, Mohammad Murtaza Mehdi
Biogerontology.2023; 24(5): 609. CrossRef
Development and Characterization of Oxidatively Responsive Thiol–Ene Networks for Bone Graft Applications
Tyler Touchet, Samuel Briggs, Lance Graul, Duncan J. Maitland
ACS Applied Bio Materials.2022; 5(6): 2633. CrossRef
Prevalence of Sarcopenia and Its Association With Diabetes: A Meta-Analysis of Community-Dwelling Asian Population
Seung Min Chung, Jun Sung Moon, Min Cheol Chang
Frontiers in Medicine.2021;[Epub] CrossRef
Association of Prx4, Total Oxidant Status, and Inflammatory Factors with Insulin Resistance in Polycystic Ovary Syndrome
Sahar Mazloomi, Nasrin Sheikh, Marzieh Sanoee Farimani, Shamim Pilehvari, Raffaele Pezzani
International Journal of Endocrinology.2021; 2021: 1. CrossRef
Plants Secondary Metabolites as Blood Glucose-Lowering Molecules
Mayadah Bashir Shehadeh, Ghadeer A. R. Y. Suaifan, Ala’ Mustafa Abu-Odeh
Molecules.2021; 26(14): 4333. CrossRef
An Epidemiological Study Report on the Antioxidant and Phenolic Content of Selected Mediterranean Functional Foods, Their Consumption Association with the Body Mass Index, and Consumers Purchasing Behavior in a Sample of Healthy Greek Adults
Aikaterini Kandyliari, Ioannis-Nektarios Elmaliklis, Olga Kontopoulou, Marianna Tsafkopoulou, Georgios Komninos, Christina Ntzatha, Andreas Petsas, Haralabos C. Karantonis, Antonios E. Koutelidakis
Applied Sciences.2021; 11(17): 7818. CrossRef
Sterculia tragacantha Lindl Leaf Extract Ameliorates STZ-Induced Diabetes, Oxidative Stress, Inflammation and Neuronal Impairment
Amos Sunday Onikanni, Bashir Lawal, Augustine O Olusola, Janet O Olugbodi, Saidu Sani, Basiru Olaitan Ajiboye, Omotayo B Ilesanmi, Mohammed Alqarni, Gomaa Mostafa-Hedeab, Ahmad J Obaidullah, Gaber El-Saber Batiha, Alexander TH Wu
Journal of Inflammation Research.2021; Volume 14: 6749. CrossRef
Methionine sulfoxide reductase B3 deficiency inhibits the development of diet-induced insulin resistance in mice
Hye-Na Cha, Chang-Hoon Woo, Hwa-Young Kim, So-Young Park
Redox Biology.2020; : 101823. CrossRef

First
Prev
Page of 1
Next
Last

Search