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Case report
- Successful laparoscopic surgery of accessory cavitated uterine mass in young women with severe dysmenorrhea
- Joon Cheol Park, Dong Ja Kim
- Yeungnam Univ J Med. 2021;38(3):235-239. Published online September 18, 2020
- DOI: https://doi.org/10.12701/yujm.2020.00696
- 5,833 View
- 159 Download
- 4 Crossref
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Abstract
PDF - Accessory cavitated uterine mass (ACUM) is a rare and unique condition seen in young women. We report cases of ACUMs in two patients, a 14-year-old girl and a 25-year-old woman, both with complaints of severe dysmenorrhea that had started at menarche and had progressively worsened since. A large cystic lesion was localized in the anterolateral wall of the myometrium separate from the endometrium, which was difficult to distinguish from congenital uterine anomalies. Laparoscopic excision of the ACUMs was successful and completely resolved the dysmenorrhea. Early investigation of severe dysmenorrhea in young women can provide appropriate management and relieve symptoms.
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Citations
Citations to this article as recorded by
- Accessory and cavitated uterine masses: a case series and review of the literature
S. Dekkiche, E. Dubruc, M. Kanbar, A. Feki, M. Mueller, J-Y. Meuwly, P. Mathevet
Frontiers in Reproductive Health.2023;[Epub] CrossRef - Accessory cavitated uterine malformation: Enhancing awareness about this unexplored perpetrator of dysmenorrhea
Rana Mondal, Priya Bhave
International Journal of Gynecology & Obstetrics.2023; 162(2): 409. CrossRef - Large uterine juvenile cystic adenomyoma in an adolescent
Zlatan Zvizdic, Irmina Sefic-Pasic, Nermina Ibisevic, Senad Murtezic, Semir Vranic
Journal of Pediatric Surgery Case Reports.2022; 81: 102258. CrossRef - Laparoscopic Approach to Accessory and Cavitatory Uterine Mass(ACUM): A Report of Four Patients in a Year
Kavitha Yogini Duraisamy, S. Saidarshini, Devi Balasubramaniam, Pradeepa, Divya Gnanasekaran
The Journal of Obstetrics and Gynecology of India.2022; 72(S2): 466. CrossRef
- Accessory and cavitated uterine masses: a case series and review of the literature
Original Article
- Effect of diazepam on the oxytocin induced contraction of the isolated rat uterus.
- Yoon Kee Park, Sung Ho Lee, Oh Cheol Kwon, Jeoung Hee Ha, Kwang Youn Lee, Won Joon Kim
- Yeungnam Univ J Med. 1992;9(2):359-381. Published online December 31, 1992
- DOI: https://doi.org/10.12701/yujm.1992.9.2.359
- 1,740 View
- 5 Download
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Abstract
PDF
- This study was designed to investigate the effect of diazepam on the spontaneous contraction and oxytocin induced contraction of the isolated rat uterus. Female rat (Sprague-Dawley) pretreated with oophorectomy and 4 days administration of estrogen. Weighing about 200 g, was sacrificed by cervical dislocation, and the uteruses were isolated. A longitudinal muscle strip was placed in temperature controlled (37℃) muscle chamber containing Locke's solution and myographied isometrically. Diazepam inhibited the spontaneous contraction and oxytocin induced contraction of the isolated rat uterus in a concentration-dependent manner. GABA, muscimol, a GABA A receptor agonist, bicuculline, a competitive GABA A receptor antagonist, picrotoxin, a non competitive GABA A receptor antagonist, baclofen, a GABA B receptor agonist, and delta-aminovaleric acid, a GABA B receptor antagonist, did not affect on the spontaneous and oxytocin induced contraction of the isolated rat uterus. The inhibitory actions of diazepam on the spontaneous and oxytocin induced contraction were not affected by all the GABA receptor agonists and antagonists, but exceptionally potentiated by bicuculline. This potentiation-effect by bicuculline was not antagonized by muscumol. In normal calcium PSS, addition of calcium restored the spontaneous contraction preinhibited by diazepam and recovered the contractile of oxtrocin preinhibited by diazepam. A23187, a calcium inophore, enhanced the restoration of both the spontaneous and oxytocin induced contraction by addition of calcium. In calcium-free PSS, diazepam suppressed the restoration of spontaneous motility by addition of calcium but allowed the recovery of spontaneous motility to a considerable extent. Diazepam could not inhibit some development of contractility by oxytocin in calcium-free PSS, but inhibited the increase in contractility by subsequent addition of calcium. These results suggest that the inhibitory action of diazepam on the rat uterine motility does not depend on or related to GABA receptors and that diazepam inhibits the extracellular calcium influx to suppress the spontaneous and oxytocin induced contractilities.
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