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JYMS : Journal of Yeungnam Medical Science

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Reliability and validity of free software for the analysis of locomotor activity in mice
Yoo Rha Hong, Eunsoo Moon
Yeungnam Univ J Med. 2018;35(1):63-69.   Published online June 30, 2018
DOI: https://doi.org/10.12701/yujm.2018.35.1.63
  • 8,200 View
  • 57 Download
  • 1 Crossref
AbstractAbstract PDF
Background
Kinovea software that tracking semi-automatically the motion in video screen has been used to study motion-related tasks in several studies. However, the validation of this software in open field test to assess locomotor activity have not been studied yet. Therefore, this study aimed to examine the reliability and validity of this software in analyzing locomotor activities.
Methods
Thirty male Institute Cancer Research mice were subjected in this study. The results examined by this software and the classical method were compared. Test-retest reliability and inter-rater reliability were analyzed with Pearson's correlation coefficient and intraclass correlation coefficient (ICC). The validity of this software was analyzed with Pearson's correlation coefficient.
Results
This software showed good test-retest reliability (ICC=0.997, 95% confidence interval [CI]=0.975-0.994, p<0.001). This software also showed good inter-rater reliability (ICC=0.987, 95% CI=0.973-0.994, p<0.001). Furthermore, in three analyses for the validity of this software, there were significant correlations between two methods (Pearson's correlation coefficient=0.928-0.972, p<0.001). In addition, this software showed good reliability and validity in the analysis locomotor activity according to time interval.
Conclusion
This study showed that this software in analyzing drug-induced locomotor activity has good reliability and validity. This software can be effectively used in animal study using the analysis of locomotor activity.

Citations

Citations to this article as recorded by  
  • Do It by Yourself: Larval Locomotion in the Black Soldier Fly Hermetia illucens, with a Novel “Self-Harvesting” Method to Separate Prepupae
    Daniele Giannetti, Enrico Schifani, Roberto Reggiani, Emanuele Mazzoni, Maria Cristina Reguzzi, Cristina Castracani, Fiorenza A. Spotti, Beatrice Giardina, Alessandra Mori, Donato A. Grasso
    Insects.2022; 13(2): 127.     CrossRef
The Study of Reliability and Validity of Attention Deficit Disorder Evaluation Scale-School Version(ADDES-SV).
Jin Woo Bae, Seung Douk Cheung, Jong Bum Lee, Hyung Bae Park, Jin Seung Kim, Chang Jin Song
Yeungnam Univ J Med. 1997;14(2):415-429.   Published online December 31, 1997
DOI: https://doi.org/10.12701/yujm.1997.14.2.415
  • 1,916 View
  • 11 Download
AbstractAbstract PDF
The purpose of this study was to examine the reliability and validity of attention deficit disorder evaluation scale-school version(ADDES-SV). Between October 1996 and November 1996, ADDES-SV was administered to 263 elementary school students in the second grade and between Jun 1996 and October 1996, 28 attention deficit hyperactivity disorder patients. In the reliability test, the test-retest reliability coefficient was significantly high and that of inattention was 0.88, that of impulsivity was 0.80, that of hyperactivity was 0.83 and total score was 0.83. In the reliability test by internal consistancy, the Cronbach alpha coefficient was significantly high and that of inattention was 0.98, that of impulsivity was 0.87, that of hyperactivity was 0.87(p<0.05). The half-sprit reliability coefficient by first-second half method showed high correlation and that of inattention was part 1: 0.96, part 2: 0.96 impulsivity was part 1: 0.95, part 2: 0.93, hyperactivity was part 1: 0.92, part 2: 0.94(p<0.05). Inter-rater reliability by pearson correlation coefficient was significantly high and that of inattention was 0.92, that of impulsivity was 0.87, that of hyperactivity was 0.89 and total score was 0.89. The concurrent validity between ADDES-SV and CAP scale was 0.85 in attention deficit hyperactivity disorder patient group and 0.79 in normal control group(p<0.05). In discriminant validity test between attention deficit hyperactivity disorder patient group and normal control group, the patient group showed higher score(p<0.05). The total discriminant capacity of the patient group in ADDES-SV was 94.6%. In this point of view, ADDES-SV scale showed high reliability and validity in applying to Korean subjects and was proved to be the useful screening test tool for attention deficit hyperactivity disorder research.
The Development of the Korean Form of Childhoood Attention Problem(CAP) Scale: A Study on the Reliability and Validity.
Wan Seok Seo, Jong Bum Lee, Hyung Bae Park, Hyea Soo Suh, Kwang Hun Lee, Jeong Kyn Sakong
Yeungnam Univ J Med. 1997;14(1):123-136.   Published online June 30, 1997
DOI: https://doi.org/10.12701/yujm.1997.14.1.123
  • 1,839 View
  • 1 Download
AbstractAbstract PDF
The purpose of this study was to examine the reliability and validity of a Korean form of Childhood Attention Problem(CAP) scale. CAP were administered to 98 normal elementary school students as control group and 98 attention deficit hyperactivity disorder patients. Male students showed high scores than female students in both subscale and total scores, but not statistically significant. There were no significant difference in CAP scale between male students and female students in attention deficit hyperactivity disorder patients. In the reliability test, the test-retest reliability coefficient was highly satisfactory and that of inattention subscale was 0.83, impulsivity subscale was 0.70 and total score was 0.82. In the reliability test by internal consistency, the Cronbach a coefficient was highly satisfactory and that of inattention subscale was 0.91, overactivity subscale was 0.89(p<0.05). The concurrent validity between CAP scale and ADDES-HV scale was 0.85 in attention deficit hyperactivity disorder patient group and 0.73 in normal control group(p<0.05). In discriminant validity test between attention deficit hyperactivity disorder patient group and normal control group, the patient group showed higher score(p<0.05). The total discriminant capacity of the patient group in CAP was 93.4%. In this point of view, CAP scale showed high reliability and validity in applying to Korean subjects and was proved to be the good and simple screening test tool for attention deficit hyperactivity disorder research and can help many young patient to treat early.
An Elementary School Children Screen Test for Attention Deficit Hyperactivity Disorder in Taegu City.
Heung Bae Park, Jin Sung Kim, Sang Ruyl Jang, Sung Chan Park, Hye Soo Suh, Kwang Hun Lee, Young Uck Kim, Chang Su Kim
Yeungnam Univ J Med. 1995;12(1):56-74.   Published online June 30, 1995
DOI: https://doi.org/10.12701/yujm.1995.12.1.56
  • 1,694 View
  • 1 Download
AbstractAbstract PDF
The authors applied ADDES-HV parent evaluation scale for the purpose of screeing test to 538 2nd grade elementary school students from March 1994 to May. The results were as follows: There was no differences in scores of ADHD between schools. In comparing the male and female between three school students, male students showed signifieant high scores (p<0.05) than female students in the score of ADDES-HV subscale and total. There was no significant differences in ADDES-HV scale between male students and female students in both ADHD patients and normal controls. In reliability test for test and retest, the reliability coefficient was higher satisfatorily and that of inattention was 0.80, inpulsivity was 0.69, hyperactivity was 0.63 and the total score was 0.82. In reliability test by internal consistancy, the Cronbach a coefficient of patient group was 0.85(p<0.05) and that of normal control was 0.84(p<0.05). The Concurrent validity between ADDES-HV scale and DSM- III -R scale was 0.57(p<0.05) in ADHD patient group and 0.84(p<0.05) in normal control group. In discriminant validity test between ADHD patient group and normal control, the ADHD patient group showed higher score(p<0.05). The total disciminant capacity of the patient group in ADDES-HV scale was 94.44%. When we regard the cut off point as standard deviation 1.5, the male student was 80 score and the female student was 69 score. In this point of view, ADDES-HV scale was proved to be the useful screening test tool for ADHD research and showed higher reliability and validity in applying to Korean subjects.

JYMS : Journal of Yeungnam Medical Science
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