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HOME > J Yeungnam Med Sci > Volume 29(2); 2012 > Article
Case Report A Case of Adrenocortical Carcinoma Secreting Cortisol and Aldosterone.
Jiyoon Ha, Min Kyung Kim, Yoon Jin Cha, Seung Kyu Kim, Gi Young Yun, Kwangwon Rhee, Joon Seong Park, Eun Suk Cho, Chul Woo Ahn, Jong Suk Park
Journal of Yeungnam Medical Science 2012;29(2):132-135
DOI: https://doi.org/10.12701/yujm.2012.29.2.132
Published online: December 31, 2012
1Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea. pjs00@yuhs.ac
2Department of Pathology, Yonsei University College of Medicine, Seoul, Korea.
3Department of Surgery, Yonsei University College of Medicine, Seoul, Korea.
4Department of Radiology, Yonsei University College of Medicine, Seoul, Korea.
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Adrenocortical carcinomas are rare and frequently aggressive tumors that may be functional (hormone-secreting) and may cause Cushing's syndrome or virilization, or non-functional and manifest as an abdominal mass. This paper reports the case of a 77-year-old woman with cortisol- and aldosterone-secreting adrenal carcinoma. The patient complained of general weakness, a moon face, and weight gain. She also had hypokalemia and hypertension. Her endocrinological data showed excessive aldosterone production and non-suppressible cortisol production in a low-dose dexamethasone suppresion test. Her abdominal CT showed a right adrenal mass. She underwent right adrenalectomy, and her histology revealed the presence of adrenocortical carcinoma. After adrenalectomy, her hypokalemia returned to normal and she is being treated with hydrocortisone.

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