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HOME > J Yeungnam Med Sci > Volume 21(2); 2004 > Article
Case Report Hematology A Case of Congenital Factor VII Deficiency Presented with Subacute Subdural Hematoma.
Min Kyoung Kim*, Sang Jun Shin, Kyung Ok Kim, Kyung Hee Lee, Myung Soo Hyun, Hee Soon Cho
Journal of Yeungnam Medical Science 2004;21:231.
DOI: https://doi.org/10.12701/yujm.2004.21.2.231
Published online: December 31, 2004
1Department of Internal Medicine, College of Medicine, Yeungnam University, Daegu, Korea. hms@medical.yu.ac.kr
2Department of Laboratory Medicine, College of Medicine, Yeungnam University, Daegu, Korea.
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A congenital factor VII deficiency is a rare disorder with an estimated incidence in the western contries of one in 500, 000. Because factor VII is important in initiation the coagulation cascade, a factor VII deficiency can result in significant bleeding with prolongation of the prothrombin time. We present a case of a factor VII deficiency with a subdural hematoma in an 18-year-old boy whose plasma activity of factor VII was < or =10%. Previously, he did not have any symptoms, such as hemarthrosis, easy bruising or bleeding after a minor trauma. He was administered fresh frozen plasma and a trephination was performed. His sister also had 51% lower level of factor VII.

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