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JYMS : Journal of Yeungnam Medical Science

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Kwan-Do Park 1 Article
Negative myoclonus associated with pregabalin
Kwan-Do Park, Min-Ku Kim, Se-Jin Lee
Yeungnam Univ J Med. 2018;35(2):240-243.   Published online December 31, 2018
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AbstractAbstract PDF
Negative myoclonus (NM) is a jerky, shock-like involuntary movement caused by a sudden, brief interruption of muscle contraction. An 80-year-old man presented with multifocal NM and confusion. Two days before the onset of NM, he commenced the intake of pregabalin at a dose of 150 mg/day for neuropathic pain. His NM resolved completely and mental status improved gradually after the administration of lorazepam intravenously and the discontinuation of pregabalin. Our study suggests that pregabalin can cause NM even in patients without a history of seizures.


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JYMS : Journal of Yeungnam Medical Science