Journal of Yeungnam Medical Science

Articles in E-pub version are posted online ahead of regular printed publication.

Communications

Physical therapy, Sports therapy, and Rehabilitation
The feasibility of conducting successful pulmonary rehabilitation in India: Manivel Arumugam, Senthilkumar Ramasamy, Pitchaimani Govindharaj, Mahendran Murugan; J Yeungnam Med Sci. 2025;42:40. Published online June 28, 2025; DOI: https://doi.org/10.12701/jyms.2025.42.40 [Epub ahead of print]

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Abstract PDF: Pulmonary rehabilitation (PR) is a highly effective evidence-based treatment with multidisciplinary and comprehensive individualized interventions that reduce morbidity by improving functional capacity and managing respiratory symptoms. It can contribute to overall wellness, reduce symptoms related to respiratory conditions, and facilitate routine work and social activities. Hence, it is a vital component of integrated care for patients with chronic respiratory diseases. In India, PR faces several challenges arising from patients, society, and hospitals. Recent evidence suggests that PR has significant benefits in chronic respiratory diseases, including reduced morbidity and mortality, improved quality of life, and cost savings. Nevertheless, it has been significantly underutilized and has not received the necessary attention in India. The lack of proper utilization of PR can be attributed to several factors, including a lack of awareness and understanding among healthcare professionals regarding its advantages, insufficient referrals to PR programs, scarcity of specialized professionals trained in PR, and a general lack of awareness among patients about its benefits. This article aims to outline the obstacles to PR, identify the factors that influence its successful implementation, and propose possible solutions to overcome these barriers.

Original article

Gastroenterology and Hepatology
Clinical association between histological activity at diagnosis and endoscopic response in patients with ulcerative colitis: a retrospective study: Jae-Sung Yoo, Kyeong Ok Kim, Min Cheol Kim, Byung Ik Jang; J Yeungnam Med Sci. 2025;42:39. Published online June 22, 2025; DOI: https://doi.org/10.12701/jyms.2025.42.39 [Epub ahead of print]

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Abstract PDF: Background
Histological activity in ulcerative colitis (UC) has been accepted to be associated with clinical outcomes. This study aimed to investigate the association between the histological activity at diagnosis and endoscopic findings, either at diagnosis or at the first follow-up, in patients with UC.
Methods
Through a retrospective review of 1 year of medical records, this study evaluated the association between histological and endoscopic activity in 51 patients newly diagnosed with UC at our hospital between March 2015 and February 2022. The Nancy histological index was used to assess histological activity, classifying patients into low (0–2) and high (3–4) groups. The Mayo Endoscopic Subscore and the Ulcerative Colitis Endoscopic Index of Severity (UCEIS) were used for endoscopic activity scoring.
Results
At diagnosis, UCEIS demonstrated no statistically significant difference histologically (p=0.065), and histological and endoscopic activities were not significantly correlated (r=0.18, p=0.200). During the first follow-up, 40 patients (78.4%) exhibited low histological activity, and the number of patients with high histological activity decreased after treatment. The first follow-up endoscopy revealed that 30 patients (58.8%) achieved an endoscopic response, including 9 (56.2%) and 21 patients (60.0%) in the high and low groups, respectively, with no significant difference (p=0.800). However, the high group at diagnosis demonstrated a positive correlation with UCEIS endoscopic activity during the first follow-up (r=0.37, p<0.001).
Conclusion
High histological activity at diagnosis was positively correlated with endoscopic activity at the first follow-up. More active care should be provided to patients with high histological activity during diagnosis.

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Physical therapy, Sports therapy, and Rehabilitation
Intrameniscal ossicle: an overlooked cause of knee pain: Berkay Yalçınkaya, Ahmet Furkan Çolak, Murat Kara; J Yeungnam Med Sci. 2025;42:38. Published online June 17, 2025; DOI: https://doi.org/10.12701/jyms.2025.42.38 [Epub ahead of print]

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Review article

Radiation Oncology
Radiation therapy in the treatment of pancreatoblastoma: a narrative review: Atsuto Katano; J Yeungnam Med Sci. 2025;42:37. Published online June 16, 2025; DOI: https://doi.org/10.12701/jyms.2025.42.37 [Epub ahead of print]

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Abstract PDF: Pancreatoblastoma is an extremely rare pediatric pancreatic tumor that primarily affects children <10 years of age, with a mean age of onset of 5 years. Risk factors such as vascular and lymph node involvement often lead to incomplete resection, necessitating a multidisciplinary approach. Despite these strategies, the role of radiotherapy in the management of pancreatoblastoma remains unclear. A quantitative literature search of the PubMed database was performed to identify relevant case reports and series that explicitly documented the use of radiotherapy for pancreatoblastoma. The search covered the period from January 1986 to November 2024. Of the 36 records retrieved, seven case reports comprising eight patients fulfilled the inclusion criteria. Six patients underwent radiotherapy at the primary tumor site with external beam therapy doses ranging from 36 to 46.2 Gy. Intraoperative radiotherapy was also administered in two cases, with doses of 15 and 20 Gy. Additionally, stereotactic radiotherapy was administered to two patients with intracranial metastases, demonstrating its effectiveness in managing brain metastases. Although the role of radiotherapy in pancreatoblastoma remains ambiguous, it demonstrates promise in cases of incomplete resection, recurrence, or non-resectable disease. However, pediatric patients require careful consideration because of potential long-term side effects. Further research is required to optimize radiotherapy protocols and integrate emerging therapies.

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