Skip Navigation
Skip to contents

JYMS : Journal of Yeungnam Medical Science

Indexed in: ESCI, Scopus, PubMed,
PubMed Central, CAS, DOAJ, KCI
FREE article processing charge
OPEN ACCESS
SEARCH
Search

Most download

Page Path
HOME > Browse Articles > Most download
193 Most download
Filter
Filter
Article category
Keywords
Publication year
Authors
Funded articles

Most-download articles are from the articles published in 2022 during the last 3 months.

Review article
Ultrasound imaging and guidance in the management of myofascial pain syndrome: a narrative review
Wei-Ting Wu, Ke-Vin Chang, Vincenzo Ricci, Levent Özçakar
J Yeungnam Med Sci. 2024;41(3):179-187.   Published online June 17, 2024
DOI: https://doi.org/10.12701/jyms.2024.00416
  • 943 View
  • 185 Download
AbstractAbstract PDF
Myofascial pain syndrome (MPS) is a common musculoskeletal disorder characterized by muscle pain, tenderness, and trigger points. Ultrasonography has emerged as a key tool for diagnosing and treating MPS owing to its ability to provide precise, minimally invasive guidance. This review discusses the use of ultrasonography in various approaches to evaluate and manage MPS. Studies have shown that shear-wave sonoelastography can effectively assess muscle elasticity and offer insights into trapezius stiffness in patients with MPS. Ultrasound-guided interfascial hydrodissection, especially with visual feedback, has demonstrated effectiveness in treating trapezius MPS. Similarly, ultrasound-guided rhomboid interfascial plane blocks and perimysium dissection for posterior shoulder MPS have significantly reduced pain and improved quality of life. The combination of extracorporeal shockwave therapy with ultrasound-guided lidocaine injections has been particularly successful in reducing pain and stiffness in trapezius MPS. Research regarding various guided injections, including dry needling, interfascial plane blocks, and fascial hydrodissection, emphasizes the importance of ultrasonography for accuracy and safety. Additionally, ultrasound-guided delivery of local anesthetics and steroids to the quadratus lumborum muscle has shown lasting pain relief over a 6-month period. Overall, these findings highlight the pivotal role of ultrasonography in the assessment and treatment of MPS.
Focused Review article
The pathophysiology of diabetic foot: a narrative review
Jiyoun Kim
J Yeungnam Med Sci. 2023;40(4):328-334.   Published online October 5, 2023
DOI: https://doi.org/10.12701/jyms.2023.00731
  • 7,869 View
  • 540 Download
  • 3 Web of Science
  • 4 Crossref
AbstractAbstract PDF
An aging population and changes in dietary habits have increased the incidence of diabetes, resulting in complications such as diabetic foot ulcers (DFUs). DFUs can lead to serious disabilities, substantial reductions in patient quality of life, and high financial costs for society. By understanding the etiology and pathophysiology of DFUs, their occurrence can be prevented and managed more effectively. The pathophysiology of DFUs involves metabolic dysfunction, diabetic immunopathy, diabetic neuropathy, and angiopathy. The processes by which hyperglycemia causes peripheral nerve damage are related to adenosine triphosphate deficiency, the polyol pathway, oxidative stress, protein kinase C activity, and proinflammatory processes. In the context of hyperglycemia, the suppression of endothelial nitric oxide production leads to microcirculation atherosclerosis, heightened inflammation, and abnormal intimal growth. Diabetic neuropathy involves sensory, motor, and autonomic neuropathies. The interaction between these neuropathies forms a callus that leads to subcutaneous hemorrhage and skin ulcers. Hyperglycemia causes peripheral vascular changes that result in endothelial cell dysfunction and decreased vasodilator secretion, leading to ischemia. The interplay among these four preceding pathophysiological factors fosters the development and progression of infections in individuals with diabetes. Charcot neuroarthropathy is a chronic and progressive degenerative arthropathy characterized by heightened blood flow, increased calcium dissolution, and repeated minor trauma to insensate joints. Directly and comprehensively addressing the pathogenesis of DFUs could pave the way for the development of innovative treatment approaches with the potential to avoid the most serious complications, including major amputations.

Citations

Citations to this article as recorded by  
  • Diabetic foot – prevention and control challenges
    Vitorino Modesto dos Santos, Taciana Arruda Modesto Sugai, Lister Arruda Modesto dos Santos
    Belize Journal of Medicine.2024;[Epub]     CrossRef
  • Treatment of Morganella morganii-Associated Non-healing Diabetic Foot Ulcer With Vaporous Hyperoxia Therapy: A Case Report
    Afrah S Abedi, Jacob L McElroy, Vladimir Valencia, Rachel M Worcester, Zhi J Yu
    Cureus.2024;[Epub]     CrossRef
  • Integrated genetic analysis of diabetic complications: Bioinformatics insights into foot ulcers, neuropathy and peripheral artery disease
    Jiaru Liang, Xiaoyang Gong, Xuyang Hu, Chong You, Jiaqi Zhou, Yuling Gao, Junwei Zong, Yong Liu
    International Wound Journal.2024;[Epub]     CrossRef
  • Unveiling the challenges of diabetic foot infections: diagnosis, pathogenesis, treatment, and rehabilitation
    Chul Hyun Park
    Journal of Yeungnam Medical Science.2023; 40(4): 319.     CrossRef
Imagery
"Nostalgia"
J Yeungnam Med Sci. 2024;41(1):i.   Published online March 17, 2023
DOI: https://doi.org/10.12701/jyms.2023.00213
  • 1,335 View
  • 274 Download
PDF
Editorial
Appreciation to peer reviewers in 2023
So-Young Park
J Yeungnam Med Sci. 2024;41(1):1-3.   Published online January 4, 2024
DOI: https://doi.org/10.12701/jyms.2023.01361
  • 1,215 View
  • 221 Download
PDFSupplementary Material
Focused Review article
Management of diabetic foot ulcers: a narrative review
Jahyung Kim, Otgonsaikhan Nomkhondorj, Chi Young An, Ye Chan Choi, Jaeho Cho
J Yeungnam Med Sci. 2023;40(4):335-342.   Published online September 22, 2023
DOI: https://doi.org/10.12701/jyms.2023.00682
  • 4,001 View
  • 304 Download
  • 3 Web of Science
  • 4 Crossref
AbstractAbstract PDF
Diabetic foot ulcers (DFUs) are among the most serious complications of diabetes and are a source of reduced quality of life and financial burden for the people involved. For effective DFU management, an evidence-based treatment strategy that considers the patient's clinical context and wound condition is required. This treatment strategy should include conventional practices (surgical debridement, antibiotics, vascular assessment, offloading, and amputation) coordinated by interdisciplinary DFU experts. In addition, several adjuvant therapies can be considered for nonhealing wounds. In this narrative review, we aim to highlight the current trends in DFU management and review the up-to-date guidelines.

Citations

Citations to this article as recorded by  
  • Kick-Starting Wound Healing: A Review of Pro-Healing Drugs
    Bethany L. Patenall, Kristyn A. Carter, Matthew R. Ramsey
    International Journal of Molecular Sciences.2024; 25(2): 1304.     CrossRef
  • Sequence analysis of microbiota in clinical human cases with diabetic foot ulcers from China
    Ying Li, Li Zhang, Meifang He, Yuebin Zhao
    Heliyon.2024; 10(14): e34368.     CrossRef
  • The future of diabetic wound healing: unveiling the potential of mesenchymal stem cell and exosomes therapy
    Sara Memarpour
    American Journal of Stem Cells.2024; 13(2): 87.     CrossRef
  • Unveiling the challenges of diabetic foot infections: diagnosis, pathogenesis, treatment, and rehabilitation
    Chul Hyun Park
    Journal of Yeungnam Medical Science.2023; 40(4): 319.     CrossRef
Review articles
Current diagnosis and treatment of vestibular neuritis: a narrative review
Chang Hoon Bae, Hyung Gyun Na, Yoon Seok Choi
J Yeungnam Med Sci. 2022;39(2):81-88.   Published online August 9, 2021
DOI: https://doi.org/10.12701/yujm.2021.01228
  • 65,535 View
  • 505 Download
  • 9 Web of Science
  • 13 Crossref
AbstractAbstract PDF
Vertigo is the sensation of self-motion of the head or body when no self-motion is occurring or the sensation of distorted self-motion during an otherwise normal head movement. Representative peripheral vertigo disorders include benign paroxysmal positional vertigo, Ménière disease, and vestibular neuritis. Vestibular neuritis, also known as vestibular neuronitis, is the third most common peripheral vestibular disorder after benign paroxysmal positional vertigo and Ménière disease. The cause of vestibular neuritis remains unclear. However, a viral infection of the vestibular nerve or ischemia of the anterior vestibular artery is known to cause vestibular neuritis. In addition, recent studies on immune-mediated mechanisms as the cause of vestibular neuritis have been reported. The characteristic clinical features of vestibular neuritis are abrupt true-whirling vertigo lasting for more than 24 hours, and no presence of cochlear symptoms and other neurological symptoms and signs. To accurately diagnose vestibular neuritis, various diagnostic tests such as the head impulse test, bithermal caloric test, and vestibular-evoked myogenic potential test are conducted. Various treatments for vestibular neuritis have been reported, which are largely divided into symptomatic therapy, specific drug therapy, and vestibular rehabilitation therapy. Symptomatic therapies include generalized supportive care and administration of vestibular suppressants and antiemetics. Specific drug therapies include steroid therapy, antiviral therapy, and vasodilator therapy. Vestibular rehabilitation therapies include generalized vestibular and customized vestibular exercises.

Citations

Citations to this article as recorded by  
  • Vestibular function is associated with immune inflammatory response
    Zhaohui Song, Yuchuan Ding, Nathan Sim, Ho Jun Yun, Jing Feng, Pan Gu, Xiaokun Geng
    Reviews in the Neurosciences.2024; 35(3): 293.     CrossRef
  • Prevalence of Scarpa’s ganglion enhancement on high-resolution MRI imaging
    Clayton Siminski, John C Benson, Matthew L Carlson, John I Lane
    The Neuroradiology Journal.2024; 37(3): 332.     CrossRef
  • Vestibular rehabilitation for peripheral vestibular hypofunction: an interdisciplinary consensus
    N.L. Kunelskay, G.E. Ivanova, E.V. Baybakova, A.L. Guseva, V.A. Parfenov, M.V. Zamergrad, O.V. Zaitseva, O.A. Melnikov, A.A. Shmonin, M.N. Maltseva
    Vestnik otorinolaringologii.2024; 89(1): 52.     CrossRef
  • A Review of Calcitonin Gene-Related Peptide and Its Implications for Vestibular Disorders
    Richard Baron, Kristen K. Steenerson
    Current Treatment Options in Neurology.2024; 26(6): 203.     CrossRef
  • Evolution of Hyperventilation-Induced Nystagmus in Acute Unilateral Vestibulopathy—Interpretative Model and Etiopathogenetic Hypotheses
    Francesco Frati, Alessandra D’Orazio, Valeria Gambacorta, Giacomo Ciacca, Giampietro Ricci, Mario Faralli
    Audiology Research.2024; 14(3): 442.     CrossRef
  • Evaluating the impact of COVID-19 on vertigo and hearing impairment: A post-recovery analysis
    Sarah Alshehri, Khalid A. Alahmari
    Medicine.2024; 103(27): e38819.     CrossRef
  • Vertigo in the Setting of COVID-19 Infection: A Case Report
    Sanjana Devaragudi, Mohit Gupta
    Cureus.2023;[Epub]     CrossRef
  • Hospital Admission Profile Related to Inner Ear Diseases in England and Wales
    Esra’ O. Taybeh, Abdallah Y. Naser
    Healthcare.2023; 11(10): 1457.     CrossRef
  • Symptom of vertigo and dizziness in patients with COVID-19
    E. V. Isakova
    Russian neurological journal.2023; 28(4): 5.     CrossRef
  • VESTIBULAR NEURONITIS: A CLINICAL EXAMPLE OF THE COURSE OF THE DISEASE USING BIOFEEDBACK (BOS)
    Geraskina M.M., Razzhivina K.S., Ustinov S.A.
    "Medical & pharmaceutical journal "Pulse".2023; : 30.     CrossRef
  • Acute vestibular neuritis: A rare complication after the adenoviral vector-based COVID-19 vaccine
    Hamze Shahali, Ramin Hamidi Farahani, Parham Hazrati, Ebrahim Hazrati
    Journal of NeuroVirology.2022; 28(4-6): 609.     CrossRef
  • A Holistic Approach to a Dizzy Patient: A Practical Update
    Ioannis Koukoulithras, Gianna Drousia, Spyridon Kolokotsios, Minas Plexousakis, Alexandra Stamouli, Charis Roussos, Eleana Xanthi
    Cureus.2022;[Epub]     CrossRef
  • Identification of hub genes and pathophysiological mechanism related to acute unilateral vestibulopathy by integrated bioinformatics analysis
    Yajing Cheng, Jianrong Zheng, Ying Zhan, Cong Liu, Bihua Lu, Jun Hu
    Frontiers in Neurology.2022;[Epub]     CrossRef
Failed back surgery syndrome—terminology, etiology, prevention, evaluation, and management: a narrative review
Jinseok Yeo
J Yeungnam Med Sci. 2024;41(3):166-178.   Published online June 10, 2024
DOI: https://doi.org/10.12701/jyms.2024.00339
  • 911 View
  • 49 Download
AbstractAbstract PDF
Amid the worldwide increase in spinal surgery rates, a significant proportion of patients continue to experience refractory chronic pain, resulting in reduced quality of life and escalated healthcare demands. Failed back surgery syndrome (FBSS) is a clinical condition characterized by persistent or recurrent pain after one or more spinal surgeries. The diverse characteristics and stigmatizing descriptions of FBSS necessitate a reevaluation of its nomenclature to reflect its complexity more accurately. Accurate identification of the cause of FBSS is hampered by the complex nature of the syndrome and limitations of current diagnostic labels. Management requires a multidisciplinary approach that may include pharmacological treatment, physical therapy, psychological support, and interventional procedures, emphasizing realistic goal-setting and patient education. Further research is needed to increase our understanding, improve diagnostic accuracy, and develop more effective management strategies.
Original article
Effect of pitavastatin on erythrocyte membrane fatty acid content in patients with chronic kidney disease: two-arm parallel randomized controlled trial
Minna Kim, Seong Eun Kim, Su Mi Lee, Won Suk An
J Yeungnam Med Sci. 2024;41(3):188-195.   Published online May 8, 2024
DOI: https://doi.org/10.12701/jyms.2024.00094
  • 955 View
  • 46 Download
AbstractAbstract PDFSupplementary Material
Background
Statins reduce the risk of cardiovascular events in patients with chronic kidney disease (CKD). Although diabetes mellitus (DM) is a reported side effect of statin treatment, some studies have indicated that pitavastatin does not cause DM. The present study investigated the effect of pitavastatin on the fatty acid (FA) content of erythrocyte membranes, which affects the occurrence of DM and cardiovascular diseases. In addition, changes in adiponectin and glycated hemoglobin (HbA1c) levels were evaluated after pitavastatin treatment.
Methods
A total of 45 patients were enrolled, 28 of whom completed the study. Over 24 weeks, 16 patients received 2 mg pitavastatin and 12 patients received 10 mg atorvastatin. Dosages were adjusted after 12 weeks if additional lipid control was required. There were 10 and nine patients with DM in the pitavastatin and atorvastatin groups, respectively. Erythrocyte membrane FAs and adiponectin levels were measured using gas chromatography and enzyme-linked immunosorbent assay, respectively.
Results
In both groups, saturated FAs, palmitic acid, trans-oleic acid, total cholesterol, and low-density lipoprotein cholesterol levels were significantly lower than those at baseline. The arachidonic acid (AA) content in the erythrocyte membrane increased significantly in the pitavastatin group, but adiponectin levels were unaffected. HbA1c levels decreased in patients treated with pitavastatin. No adverse effects were associated with statin treatment.
Conclusion
Pitavastatin treatment in patients with CKD may improve glucose metabolism by altering erythrocyte membrane AA levels. In addition, pitavastatin did not adversely affect glucose control in patients with CKD and DM.
Review article
Breakthrough pain and rapid-onset opioids in patients with cancer pain: a narrative review
Jinseok Yeo
J Yeungnam Med Sci. 2024;41(1):22-29.   Published online June 30, 2023
DOI: https://doi.org/10.12701/jyms.2023.00367
  • 5,448 View
  • 230 Download
AbstractAbstract PDF
Breakthrough pain is transitory pain that occurs despite the use of opioids for background pain control. Breakthrough pain occurs in 40% to 80% of patients with cancer pain. Despite effective analgesic therapy, patients and their caregivers often feel that their pain is not sufficiently controlled. Therefore, an improved understanding of breakthrough pain and its management is essential for all physicians caring for patients with cancer. This article reviews the definition, clinical manifestations, accurate diagnostic strategies, and optimal treatment options for breakthrough pain in patients with cancer. This review focuses on the efficacy and safety of rapid-onset opioids, which are the primary rescue drugs for breakthrough pain.
Focused Review article
Effective and appropriate use of weight loss medication in pediatric obesity: a narrative review
Yoojin Lindsey Chung
J Yeungnam Med Sci. 2024;41(3):158-165.   Published online July 2, 2024
DOI: https://doi.org/10.12701/jyms.2024.00353
  • 684 View
  • 40 Download
  • 1 Crossref
AbstractAbstract PDF
Over the past few decades, there has been a notable increase in the incidence of pediatric obesity, which is a significant public health concern. Children who are obese have a greater risk of type 2 diabetes, hypertension, dyslipidemia, polycystic ovary syndrome, obstructive sleep apnea, and adult obesity. Lifestyle modification therapy is typically the initial approach to treat pediatric obesity. For patients who do not achieve success with lifestyle modification therapy alone, pharmacotherapy is the next logical treatment option. When selecting an anti-obesity medication (AOM), it is essential to first ascertain the medical background of the patient, including current medications and obesity-associated comorbidities. Evaluation of obesity phenotypes in patients may also be beneficial. AOMs for pediatric obesity include metformin, orlistat, glucagon-like peptide 1 agonists, phentermine, and the phentermine/topiramate combination. Sufficient lifestyle modification therapy should be administered before considering pharmacotherapy and continued after the initiation of AOM. To ensure healthy development, monitoring growth and puberty development during anti-obesity treatments is essential.

Citations

Citations to this article as recorded by  
  • Exploring comprehensive insights into pediatric obesity
    Yong Hee Hong
    Journal of Yeungnam Medical Science.2024; 41(3): 139.     CrossRef
Review articles
Long-term management of Graves disease: a narrative review
Hyo-Jeong Kim
J Yeungnam Med Sci. 2023;40(1):12-22.   Published online November 4, 2022
DOI: https://doi.org/10.12701/jyms.2022.00444
  • 8,293 View
  • 365 Download
  • 3 Web of Science
  • 4 Crossref
AbstractAbstract PDF
Graves disease (GD) is the most common cause of hyperthyroidism, accounting for more than 90% of cases in Korea. Patients with GD are treated with any of the following: antithyroid drugs (ATDs), radioactive iodine (RAI) therapy, or thyroidectomy. Most patients begin treatment with ATDs, and clinical guidelines suggest that the appropriate treatment period is 12 to 18 months. While RAI treatment and surgery manage thyrotoxicosis by destroying or removing thyroid tissue, ATDs control thyrotoxicosis by inhibiting thyroid hormone synthesis and preserving the thyroid gland. Although ATDs efficiently control thyrotoxicosis symptoms, they do not correct the main etiology of GD; therefore, frequent relapses can follow. Recently, a large amount of data has been collected on long-term ATDs for GD, and low-dose methimazole (MMZ) is expected to be a good option for remission. For the long-term management of recurrent GD, it is important to induce remission by evaluating the patient’s drug response, stopping ATDs at an appropriate time, and actively switching to surgery or RAI therapy, if indicated. Continuing drug treatment for an extended time is now encouraged in patients with a high possibility of remission with low-dose MMZ. It is also important to pay attention to the quality of life of the patients. This review aimed to summarize the appropriate treatment methods and timing of treatment transition in patients who relapsed several times while receiving treatment for GD.

Citations

Citations to this article as recorded by  
  • Commentary: Azathioprine as an adjuvant therapy in severe Graves’ disease: a randomized controlled open-label clinical trial
    Madhukar Mittal, Azher Rizvi
    Frontiers in Endocrinology.2024;[Epub]     CrossRef
  • Total Thyroidectomy – A Cost-effective Alternative to Anti-Thyroid Drugs in the Management of Grave's Disease
    Erivelto Volpi, Leonardo M. Volpi
    Clinical Thyroidology.2023; 35(5): 183.     CrossRef
  • Evaluation of the Abbott Alinity i Thyroid-Stimulating Hormone Receptor Antibody (TRAb) Chemiluminescent Microparticle Immunoassay (CMIA)
    Deborah J. W. Lee, Soon Kieng Phua, Yali Liang, Claire Chen, Tar-Choon Aw
    Diagnostics.2023; 13(16): 2707.     CrossRef
  • Mechanisms and Treatment Options for Hyperthyroid-Induced Osteoporosis: A Narrative Review
    Robert M Branstetter, Rahib K Islam, Collin A Toups, Amanda N Parra, Zachary Lee, Shahab Ahmadzadeh, Giustino Varrassi, Sahar Shekoohi, Alan D Kaye
    Cureus.2023;[Epub]     CrossRef
Comprehensive overview of the role of mitochondrial dysfunction in the pathogenesis of acute kidney ischemia-reperfusion injury: a narrative review
Min-Ji Kim, Chang Joo Oh, Chang-Won Hong, Jae-Han Jeon
J Yeungnam Med Sci. 2024;41(2):61-73.   Published online February 14, 2024
DOI: https://doi.org/10.12701/jyms.2023.01347
  • 1,977 View
  • 98 Download
AbstractAbstract PDF
Acute kidney ischemia-reperfusion (IR) injury is a life-threatening condition that predisposes individuals to chronic kidney disease. Since the kidney is one of the most energy-demanding organs in the human body and mitochondria are the powerhouse of cells, mitochondrial dysfunction plays a central role in the pathogenesis of IR-induced acute kidney injury. Mitochondrial dysfunction causes a reduction in adenosine triphosphate production, loss of mitochondrial dynamics (represented by persistent fragmentation), and impaired mitophagy. Furthermore, the pathological accumulation of succinate resulting from fumarate reduction under oxygen deprivation (ischemia) in the reverse flux of the Krebs cycle can eventually lead to a burst of reactive oxygen species driven by reverse electron transfer during the reperfusion phase. Accumulating evidence indicates that improving mitochondrial function, biogenesis, and dynamics, and normalizing metabolic reprogramming within the mitochondria have the potential to preserve kidney function during IR injury and prevent progression to chronic kidney disease. In this review, we summarize recent advances in understanding the detrimental role of metabolic reprogramming and mitochondrial dysfunction in IR injury and explore potential therapeutic strategies for treating kidney IR injury.
Beneficial effects of intermittent fasting: a narrative review
Dae-Kyu Song, Yong-Woon Kim
J Yeungnam Med Sci. 2023;40(1):4-11.   Published online April 4, 2022
DOI: https://doi.org/10.12701/jyms.2022.00010
  • 7,491 View
  • 386 Download
  • 4 Web of Science
  • 9 Crossref
AbstractAbstract PDF
Caloric restriction is a popular approach to treat obesity and its associated chronic illnesses but is difficult to maintain for a long time. Intermittent fasting is an alternative and easily applicable dietary intervention for caloric restriction. Moreover, intermittent fasting has beneficial effects equivalent to those of caloric restriction in terms of body weight control, improvements in glucose homeostasis and lipid profiles, and anti-inflammatory effects. In this review, the beneficial effects of intermittent fasting are discussed.

Citations

Citations to this article as recorded by  
  • Intermittent fasting and longevity: From animal models to implication for humans
    Olha Strilbytska, Svitlana Klishch, Kenneth B. Storey, Alexander Koliada, Oleh Lushchak
    Ageing Research Reviews.2024; 96: 102274.     CrossRef
  • Combined Aerobic Exercise with Intermittent Fasting Is Effective for Reducing mTOR and Bcl-2 Levels in Obese Females
    Purwo Sri Rejeki, Adi Pranoto, Deandra Maharani Widiatmaja, Dita Mega Utami, Nabilah Izzatunnisa, Sugiharto, Ronny Lesmana, Shariff Halim
    Sports.2024; 12(5): 116.     CrossRef
  • Effect of Intermittent Fasting Interventions for Treatment of Overweight and Obesity in Adults – A Systematic Review
    Teena Lal, S. J. Ajeet Arulkumar, S. Roopa
    Acta Medica International.2024; 11(1): 7.     CrossRef
  • Intermittent fasting influences immunity and metabolism
    Daniel M. Marko, Meghan O. Conn, Jonathan D. Schertzer
    Trends in Endocrinology & Metabolism.2024;[Epub]     CrossRef
  • Intermittent Fasting Improves Social Interaction and Decreases Inflammatory Markers in Cortex and Hippocampus
    Martín García-Juárez, Adamary García-Rodríguez, Gabriela Cruz-Carrillo, Orlando Flores-Maldonado, Miguel Becerril-Garcia, Lourdes Garza-Ocañas, Ivan Torre-Villalvazo, Alberto Camacho-Morales
    Molecular Neurobiology.2024;[Epub]     CrossRef
  • Impact of Intermittent Fasting and Dietary Restriction on Redox State, Energetic Metabolism, and Liver Injury in Common Bile Duct Ligation Model
    Dmitry S. Semenovich, Ljubava D. Zorova, Polina A. Abramicheva, Nadezda V. Andrianova, Andrey V. Elchaninov, Aleksandra S. Petrukhina, Irina B. Pevzner, Vasily N. Manskikh, Dmitry B. Zorov, Egor Y. Plotnikov
    Antioxidants.2024; 13(7): 835.     CrossRef
  • DOSE: a lifestyle philosophy for dementia prevention informed by drug development and epidemiology
    Timothy Daly
    Dementia & Neuropsychologia.2024;[Epub]     CrossRef
  • Maternal intermittent fasting deteriorates offspring metabolism via suppression of hepatic mTORC1 signaling
    Wenzhen Yin, Lijun Sun, Yuan Liang, Chao Luo, Tiange Feng, Yunhua Zhang, Weizhen Zhang, Yue Yin
    The FASEB Journal.2023;[Epub]     CrossRef
  • Time-Restricted Feeding and Intermittent Fasting as Preventive Therapeutics: A Systematic Review of the Literature
    Arturo P Jaramillo, Javier Castells, Sabina Ibrahimli, Luisa Jaramillo, Rebeca R Briones Andriuoli, Denisse Moncada, Jhoanny C Revilla
    Cureus.2023;[Epub]     CrossRef
Multidisciplinary approach to sarcopenia: a narrative review
Wook Tae Park, Oog-Jin Shon, Gi Beom Kim
J Yeungnam Med Sci. 2023;40(4):352-363.   Published online September 7, 2023
DOI: https://doi.org/10.12701/jyms.2023.00724
  • 3,135 View
  • 179 Download
  • 1 Web of Science
AbstractAbstract PDF
Sarcopenia is a condition in which muscle mass and strength are decreased and muscle function is impaired. It is an indicator of frailty and loss of independence in older adults. It is also associated with increased physical disability, which increases the risk of falls. As a multifactorial disease, sarcopenia is caused by a combination of factors including aging, hormonal changes, nutritional deficiencies, and physical inactivity. Understanding the underlying pathophysiology of sarcopenia and identifying its different causes is critical to developing effective prevention and treatment strategies. This review summarizes the pathophysiology, consequences, diagnostic methods, and multidisciplinary approaches to sarcopenia.
Original article
Enhancing ketamine anesthesia with midazolam and fentanyl for children’s ear surgery: a prospective randomized study
Seong Min Han, So Young Kwon, Jang Hyeok In, Jin Deok Joo
J Yeungnam Med Sci. 2024;41(3):207-212.   Published online May 23, 2024
DOI: https://doi.org/10.12701/jyms.2024.00276
  • 793 View
  • 30 Download
AbstractAbstract PDF
Background
Myringotomy with tympanostomy tube insertion (MTI) is a superficial surgical procedure used to prevent hearing loss in children with serous otitis media. Intravenous anesthesia, often ketamine, is preferred for this procedure because of its ability to induce sedation without compromising airway reflexes. However, ketamine alone may be insufficient and potentially lead to spontaneous movement during surgery. This study evaluated the effectiveness of midazolam and fentanyl as adjuvants to ketamine in reducing spontaneous movement during MTI and enhancing the quality of recovery.
Methods
This study involved two groups of 30 patients each: one group received intravenous ketamine (1.5 mg/kg) with an equal volume of normal saline (K group), while the other received a combination of midazolam, fentanyl, and ketamine (0.05 mg/kg, 1 μg/kg, and 1.5 mg/kg, respectively; MFK group). We assessed side effects, intraoperative patient movement, surgeon satisfaction, and emergence agitation scores.
Results
The MFK group exhibited significantly lower scores for patient movement (p<0.01) and emergence agitation (p<0.01) and markedly higher surgeon satisfaction scores (p<0.01) than the K group.
Conclusion
Administering a midazolam-fentanyl-ketamine combination effectively reduced spontaneous movement during surgery and emergence agitation during recovery without prolonging discharge times in children undergoing MTI.

JYMS : Journal of Yeungnam Medical Science