Journal of Yeungnam Medical Science

Volume 11(2); December 1994

Reviews

Health Promotion.: Pock Soo Kang; Yeungnam Univ J Med. 1994;11(2):195-201. Published online December 31, 1994; DOI: https://doi.org/10.12701/yujm.1994.11.2.195

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Abstract PDF: No abstract available.

Surgical Managements of Ischemic Stroke.: Byung Yon Choi; Yeungnam Univ J Med. 1994;11(2):202-212. Published online December 31, 1994; DOI: https://doi.org/10.12701/yujm.1994.11.2.202

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Abstract PDF: No abstract available.

Original Articles

The Effects of Microwave Irradiated on Rabbit's ICP.: Jin Han Park, Seong Ho Kim, Dong Ro Han, Jang Ho Bae, Oh Lyong Kim, Byung Yon Choi, Soo Ho Cho, Joon Ha Lee; Yeungnam Univ J Med. 1994;11(2):213-220. Published online December 31, 1994; DOI: https://doi.org/10.12701/yujm.1994.11.2.213

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Abstract PDF: Damages on central nervous system induced by the exposure of microwave. However, the effects of microwave on ICP are not studied yet. The ICP affected by the condition of the condition of the brain has an significant effect on vital sign. So we investigated the changes of ICP of the rabbits after exposure. Twenty four rabbits were divided into 3 groups depending on the amount of exposure to microwave. One group was composed with 8 rabbits were exposed to microwave for 10 miniutes. Other were composed to microwave for 20 miniutes, 30 miniures, respectively. Intracranial pressure on each group were measured by subdural type ICP monitoring catheter immediately, first day, 3rd day, 5th day and 7th day after exposure of microwave. Results indicates that intracranial pressure of rabbits are not affected with statistical significance by exposure of microwave.

Subependymal Giant Cell Astrocytoma in the tuberous Sclerosis.: Jin Han Park, Seong Ho Kim, Dong Ro Han, Jang Ho Bae, Sam Kyu Ko, Oh Lyong Kim, Byung Yon Choi, Soo Ho Cho; Yeungnam Univ J Med. 1994;11(2):221-229. Published online December 31, 1994; DOI: https://doi.org/10.12701/yujm.1994.11.2.221

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Abstract PDF: Tuberous sclerosis is reported rarely and is associated with systemic lesions including central nervous system, skin, heart, eye and kidney. Approximately 5-15% of individuals with tuberous sclerosis will develop brain neoplasia, almost invariably subependymal giant-cell astrocytoma (SGCA). We experienced a case of SGCA with tuberous sclerosis operated by the transcallosal approach and report with literature review.

Determinants of Successful Percutaneous Transluminal Coronary Angioplasty.: Kyo Won Choi, Jun Young Kweon, Yeung Jin Kim, Tae Il Lee, Dong Gu Shin, Young Jo Kim, Bong Sup Shim, Hyun Woo Lee, Sam Beom Lee; Yeungnam Univ J Med. 1994;11(2):230-239. Published online December 31, 1994; DOI: https://doi.org/10.12701/yujm.1994.11.2.230

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Abstract PDF: In Order to evaluate determinants of successful percutaneous transluminal coronary angioplasty (PTCA), PTCA was performed for 172 coronary arterial lesions in 120 patients(89 male, 31 female) at Yeungnam university hospital from Sep. 1992 to Aug 1993. The corinary artery luminal diameter at the site of the original stenosis was eveluated from end-diastolic frames of identical projections of the preangioplasty and immediate post angioplasty. The coronary luminal and balloon diameters were measured with using of computer measuring system. Overall success rate of 172 attempted lesions was 87.2%. Success rate of female patients was 93.5% and higher than those of male patients. According to the clinical diagnosis, success rate in stable angina was 93.7% and higher than those of post myocardial infarction angina, unstable angina and acute myocardial infarcrion. Success rate of American Heart Association type C lesion was 65.5% and lower those of type A(95.7%), type B (89.%). There was significantly difference in preangioplasty luminal stenosis, elastic recoil and length of lesion between successful PTCA group and failed PTCA group. Success rate of lesion location at a bed >45° and presence of intracoronary thrombus were lower than than those of other angiographic findings. In coclusion, primary angioplasty success was affected by specific angiographic factors, Stenosis severity, thrombus, lesion location at a bend >45°, elastic recoil, and length of lesion were the principle of determinants of coronary angioplasty success rate.

Isolation of Acid-fast bacilli from Tissues of Extrapulmonay Tuberculosis.: Jin Woo Rho, Hee Jin Choi, Hyeung Il Kim, Jin Hong Chung, Kwan Ho Lee, Hyun Woo Lee, Sam Beom Lee; Yeungnam Univ J Med. 1994;11(2):240-247. Published online December 31, 1994; DOI: https://doi.org/10.12701/yujm.1994.11.2.240

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Abstract PDF: To evaluate the isolation rate of acid-fast bacilli on Ziehl-Neelsen stain from biopsy specimens of extrapulmonary tuberculosis proven by chronic granulomatous inflammation, 286 cases of extrapulmonary tuberculosis were reviewed and the results are as follows : 1) Mean age was 27.3 years old and lymphatic tuberculosis was more prevalent in the female but others were more common in the male. 2) The most common site of extrapulmonary tuberculosis was pleura (103 cases ; 36%) followed by lymph nodes (87 cases ; 30.4%), gastrointestinal tract (27 cases ; 9.4%), skin and soft tissue (23 cases ; 8.0%), bone (19 cases ; 6.6%), urinary tract (14 cases ; 4.6%), larynx (9 cases ; 3.2%) and breast (5 cases ; 1.8%) in order of frequencies. 3) Of 286 cases, 30.4%, (87 cases) of the biopsy specimens showed acid fast bacilli on microscopy. The isolation rate according to the sites was slightly higher in breast and lymph nodes as 3 of 5 cases (60.0%) and 35 of 87 cases (40.2%) respectively, and followed by 3 of 9 cases (33.3%) in the larynx, 4 of 13 cases (30.8%) in the urinary tract, 5 of 19 cases (26.3%) in the bone, 7 of 27 cases (25.9%) in the gastrointestinal tract, 26 of 103 cases (25.2%) in the pleura, and 4 of 23 cases (17.4%) in the skin and soft tissue, in order of frequencies. 4) The prevalence of extrapulmonary tuberculosis associated with pulmonary tuberculosis on chest X-ray was 85 of 286 cases (29.7%).

Motor Evoked Potential Study with Magnetic Stimulation In Ischemic Stroke Patients.: Seong Min Kim, Sang Dug Suh, Jun Lee, Jung Sang Hah; Yeungnam Univ J Med. 1994;11(2):248-261. Published online December 31, 1994; DOI: https://doi.org/10.12701/yujm.1994.11.2.248

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Abstract PDF: This study was undertaken to evaluate the clinical usefulness of magnetic motor evoked potential (MEP) in the diagnosis of stroke and predicting the motor improvement following stroke. The cortical, cervical and lumbar stimulations were performed in the case of 24 healthy controls and 24 to a target muscle between after transcranial stimulation and after cervical or lumbar stimulation. There was no case showing no response in controls. But in 11 out of 24 ischemic patients, we could not get cortical MEP. Mean CMCT of abductor pollicis brevis muscle was not significantly different in controls and stroke patients in whom MEPs were recorded. There were significant differences between mean CMCT of normal controls and that of stroke patients showing MEPs in AH Muscle. MEP Results from testing the stroke patients were correlated with site of lesion, degree of motor weakness and motor improvement after 1 to 2 months. These results suggest that magnetic MEP is easy and useful in electrophysiological test of central motor pathway and is useful indicator for representing the motor weakness and predicting the motor outcome in acute ischemic stroke patients.

The Change of Glutathione Metabolism in Liver and Kidney of Cisplatin treated Rats.: Seong Yong Kim, Jae Yong Chung, Jae Ryong Kim, Jung Hye Kim; Yeungnam Univ J Med. 1994;11(2):262-269. Published online December 31, 1994; DOI: https://doi.org/10.12701/yujm.1994.11.2.262

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Abstract PDF: Glutathione (GSH) is a well-known antioxidative cellular component which is ubiquitous in nature. Several enzymes involved in GSH metabolism and recycling have been found to play important roles in detoxification of xenobiotics and free radicals. In this study, total GSH content, activity of GSH peroxidase and GSH reductase were measured in liver and kidney of cisplatin treated rats. Total GSH content (mM/g protein) of liver was higher in cisplatin treated rats (1.51±0.28) than of nontreated control (0.95±0.28), and in kidney, it was also higher in cisplatin treated rats (0.87±0.20) than that of control (0.68±0.14). The activity of GSH peroxidase (µM/mg protein/min) was lower in liver of cisplatin treated rats (348.0±18.54) than that of control (415.5±53.15), in kidney it was increase din cisplatin treated rats (380.5±51.86) compared to control (327.3±20.36). The activity of GSH reductase (µM/mg protein/min) was higher in liver of cisplatin treated rats (3.09±0.88) than that of control (2.28±0.61), in kidney it was also higher in cisplatin treated rats (8.50±2.62) than that of control (3.30±1.10). In summary, detoxification of ciplatin was revealed lesser effect in kidney as show increasion of GSH peroxidase and reductase and detoxification of cisplatin was expressed effectively in liver by increasing of GSH content and decreasing GSH peroxidase.

The Effect of the Local Anesthetic Cream in Alleviating Pain form Vaccination.: Sang Duk Kim, Son Moon Shin, Yong Hoon Park; Yeungnam Univ J Med. 1994;11(2):270-276. Published online December 31, 1994; DOI: https://doi.org/10.12701/yujm.1994.11.2.270

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Abstract PDF

To evaluate the effect of a new topical anesthetic cream (EMLA : Eutectic mixture of local anesthetics) on reducing pain associated with DPT vaccination, we conducted a clinical observation on eighty infants who were brought to well baby clinic of Yeungnam University Hospital for DPT vaccination. 80 Infants, who were between 2 months and 8 months in age, were divided into two groups. EMLA treated group and control group. Male to femle sex ratio was 1.4 to 1. EMLA cream was applied 60 minutes before DPT vaccination, the effect of reducing pain was assessed by using McGrath's face scale, Oucher pain scale and modified behavioral pain scale (MBPS) and also evaluated by measuring the duration and time of crying (the time of the first crying after iniection, duration of the first crying, total duration of crying). The scores of those scales were lower in EMLA treated group than in control group significantly (P<0.01 in McGrath's face scale. MBPS and p<0.05 in Oucher pain scale). There was no difference in the time of the first crying after vaccination in both groups. The duration of the first crying was shorter in EMLA treated group than control group of crying was also shorter in EMLA treated group (EMLA treated group 9.0±12.5 sec, p<0.05). Transient skin erythema was noted in 5 infants after EMLA application, but no other adverse effects were observed. We conclude that the application of EMLA cream before vaccination seems to be an effective and safe way to reduce the pain from vaccination, but it takes usually 60 minutes to get the anesthetic effect of EMLA and it is expensive, so EMLA cream can not be recommended in routine vaccination in infants now.

Citations

Citations to this article as recorded by

Effect of vapocoolant spray and EMLA cream upon DPT vaccination pain in infants
Gunja Jang, Eunyoung Jeon, Eunsil Lee
Journal of the Korean Data and Information Science Society.2014; 25(4): 705. CrossRef
The effects of EMLA cream on pain responses of preschoolers
Se Na Ahn, Joohyun Lee, Hae Won Kim, Sook Bin Im, Byung Sun Cho, Hye Young Ahn
Open Journal of Nursing.2013; 03(08): 1. CrossRef

The Effect of Extracapsular Cataract Extraction and Posterior Chamber Lens Implantation on Intraocular Pressure.: Soon Cheol Cha, Kyoo Won Lee; Yeungnam Univ J Med. 1994;11(2):277-283. Published online December 31, 1994; DOI: https://doi.org/10.12701/yujm.1994.11.2.277

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Abstract PDF: We studied the change in intraocular pressure (IOP) in 15 consecutive cataract patients who underwent extracapsular cataract extraction and posterior chamber lens implantation between Feb. 1993 and Apr. 1993 to evaluate the effect of this surgery on postoperative IOP. To evaluate the clinical usefulness of non-contact tonometer, the intraocular pressures were measured with Kowa non-contact tonometer (TM-2000, Japan) as well as Goldmann applanation tonometer. There was a decrease in IOP of 3.4±2.9mmHg (p<0.001) 3 months after this surgery and the intraocular pressure differences between pseudophakic eyes and contralateral phakin eyes at 3 months postoperatively were 2.4±3.8mmHg (p<0.05). The correlation coefficient between non-contact tonometer and Goldmann tonometer was 0.8876 (p=0.001) in the postoperative 76 eyes. Therefore, out results suggest that extracapsular cataract extraction and posterior chamber lens implantation alone can be a useful surgical method in cataract patient with ocular hypertension, and non-contact tonometer was relatively accurate in measuring the postoperative intraocular pressure.

The Early Result of Anterior Rotational Osteotomy in the Treatment of Osteonecrosis of the Femoral Head.: Sae Dong Kim, Duk Seop Shin, Woo Seok Jang; Yeungnam Univ J Med. 1994;11(2):284-292. Published online December 31, 1994; DOI: https://doi.org/10.12701/yujm.1994.11.2.284

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Abstract PDF: In transtrochanteric rotational osteotomy to treat osteonecrosis of the femoral head, the necrotic superior anterior femoral head is rotated anteriorly around the longitudinal neck axis so that the weight bearing force is transferred to the intact posterior surface. The ratio of transposed intact articular surface of the femoral head to the weight-bearing surface of the acetabulum on postoperative anteroposterior view of the hip roentgenograph is the most important indicator of the prognosis. During the period from December 1992 to June 1994, we treated 31 hips in 28 patients who were indicated for the anterior rotational osteotomy among the patients of osteoncrosis of the femoral head. Among the patients, male were 27 and female was one. Age distribution was from 13 to 62 years old and mean age was 44.3. According to the Ficat and Arlet classification, II A was most in number as 16 II B was 7 and III was 8. As their etiolgic factors, alcohol was most in number as 18, steroid was 3, idiopathic was 5 and trauma was 2. The mean rate of the intact area of the posterior part of the femoral head to the total articular surface on the preoperative lateral view of the hip roentgenograph was 41.8%. The mean ratio of transposed intact articular surface of the femoral head to the weight bearing surface of the acetabulum was 53.8% Fixation devices were screws or dynamic hip screw.

Effect of Imipramine on the Contractility of Single Cells Isolated for Canine Detrusor.: Chan Wook Huh, Kang Youn Lee, Won Joon Kim; Yeungnam Univ J Med. 1994;11(2):293-302. Published online December 31, 1994; DOI: https://doi.org/10.12701/yujm.1994.11.2.293

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Abstract PDF: The objective of this study was to establish a good methodology to isolate single smooth muscle cells that are alive and respond properly to pharmacological agents. Canine urinary bladders were employed as the source of single cells, and acetylcholine, atropine and imipramine were used as indicators of pharmacological responsiveness. Imipramine, an antidepressant drug exhibited the anticholinergic and calcium antagonizing properties on rat detrusor muscle. To establish a control value for a further experiment to elucidate the mechanism of action of imipramine on detrusor muscle, we measured the concentration-response of single cells to acetylcholine in the presesnce of imipramine by length of the cells and compared the result with the response in the presence of atropine. Tiny chops of smooth muscle taken from anesthetized canine urinary bladder were incubated in collagenase solution at 36℃ for 17-20 minutes. The collagenase solution included collagenase 1.2 mg/ml, soybean tryspin inhibitory 0.08 mg/ml, bovine serum albumin 2% in 10 ml Krebs-Henseleit buffer solution aerated with a consistent breeze of 95/5% O2/CO2 to maintain the pH at 7.4. After washing with plain K-H solution on 450 mesh, cells were dissociated from the digested tissue for 12-15 minutes. Cell suspension was transfered in 5 ml test tubes and acetylcholine was added for the final concentration to be 10⁻¹⁴~10⁻⁹M. To find the optimal time to fix the cells to determine the contractile responses, 1% acrolein was added 5, 10, 20, 30, 60 and 120 seconds after the administration of ACh. The length of cells fixed by acrolein were measured by microscaler vis CCTV camers on phaes-contrast microscope. The average length of 50 cells from a slide glass was taken as the value of a sample at the very concentration point. Single cells were isolated from canine detrusor. The length of untreated cells varied from 82 µm to 94 µm. The maximal response to actylcholine 10E-9M was accomplished within 5 seconds of exposure, and the shortening was 19±3%. Atropine reduced the contraction of the cells concentration-dependently. Lmipramine which exerts a cholinergic blocking action on some smooth muscles also reduced the contraction concentration-dependently and by a similar pattern as atropine. These findings document that imipramine may exerts a cholinergic blocking activity in the single smooth muscle cells isolated from canine urinary bladder.

Resurfacing of the Open Wound of the Hand with Free Arterialized Venous Falp.: Sang Hyun Woo, Seong Eon Kim, Jae Ho Jeong, Kyung Ho Lee, Jung Hyun Seul; Yeungnam Univ J Med. 1994;11(2):303-313. Published online December 31, 1994; DOI: https://doi.org/10.12701/yujm.1994.11.2.303

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Abstract PDF: Since introduction of venous flap in 1980, many experimental studies and clinical applications of various kinds of venous flaps were reported. Venous flap has the following advantages : (1) nonbulky and goo-quality of flap (2) long & large vascular pedicle (3) easy & rapid elevation of flap (4) no sacrifice of major arteries (5) a single operative field. But, we also have some disadvantages of difficult handling of the pliable veins and the tmcertainty of flap survival. For the better result we had to design the size of the flap larger than that of defect and increase the number of draining vein to reduce the postoperative edema of the flap. We have treated the defects of soft tissue of the hand using free arterialized venous flap from the flexor aspect of the forearm & had an excellent results.

Effect of GABA on the Contractility of Canine Trachealis Muscle.: Cheol Hoe Koo, Oh Chul Kwon, Eun Mee Choi, Kang Youn Lee, Won Joon Kim; Yeungnam Univ J Med. 1994;11(2):314-322. Published online December 31, 1994; DOI: https://doi.org/10.12701/yujm.1994.11.2.314

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Abstract PDF: This study aimed to investigate the existence of GABA receptor and the mechanisms of action of GABA and diazepam of the trachealis muscle isolated from dog. Horizontal muscle strips of 2mm×15mm were prepared from canine trachea, and isometric myography in isolated muscle chamber bubbled with 95/5%-O₂/CO₂ at 36℃, at the pH of 7.4 was performed. Muscle strips contracted responding to the electrical field stimulation (ESP) by 2~20 Hz, 20 msec, monophasic square wave of 60 VDC. GABA and diazepam suppressed the EFS-induced contractions to the similar extent, significantly. (p<0.05). Bicuculline, a GABA(A) receptor antagonist blocked both GABA- and diazepam-inhibitions; but DAVA, a GABA(B) receptor antagoinst did not affect either of them. These results suggest than in the canine trachealis muscle, there may be only GABA(A) receptor, and GABA and diazepam inhibit the contractility via GABA(A) receptor.

The Distribution and Trend of Malocclusion Patients Visited at Department of Dentistry in Orthodontics.: Jong Sup Kim, Jin Ho Park, Hong Sik Yun, Nan Hi Im, Byung Rho Chin, Hee Kyung Lee; Yeungnam Univ J Med. 1994;11(2):323-331. Published online December 31, 1994; DOI: https://doi.org/10.12701/yujm.1994.11.2.323

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Abstract PDF

1.050 patients who visited orthodontic dental department from 1983 to 1994, were surveyed on the yearly tendency of orthodontic patient distribution and state by means of Angle's classification. The results were as follows : 1. There was increased visiting rate of patient per year and higher visiting rate in female than in male. 2. 8-15 age group was 61.4% in total visiting patients and over 20 age group was 18.5%, under 7 age group was 8.1%. 3. Class I malocclusion was 42.2%, class II div 1 was 22.5%, class II-2 was 3.9%, class III was 29.1% and cleft lip & palate was 2.0% in total visiting patient. 4. As showed the living distribution, Namgu and Susunggu's patients were 43.7% of the total patients. 5. There was increased tendency for the number of the patient to be received orthognathic surgery.

Citations

Citations to this article as recorded by

The effect of a malocclusion status of a patient for orthodontic treatment, a fee for orthodontic and oral health behavior on orthodontic satisfaction
In-Ho Jeong, Sook-Jeong Lee, Si-Duk Lim, Byung-Sik Kim, Young-Dae Park, Ji-Young Park, Jong-Hwa Lee
Journal of Korean Acedemy of Dental Technology.2013; 35(4): 395. CrossRef

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