Journal of Yeungnam Medical Science

Case Reports

Dermatomyositis sine dermatitis, a rare phenotype of idiopathic inflammatory myopathy: Jin Sung Park, Ji Young Park; Yeungnam Univ J Med. 2017;34(1):137-139. Published online June 30, 2017; DOI: https://doi.org/10.12701/yujm.2017.34.1.137

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Dermatomyositis (DM) is characterized by progressive proximal limb weakness and typical skin manifestations. The histological findings that show perifascicular atrophy and deposition of membrane attack complex are pathognomic features of DM. Dermatomyositis is categorized into classical DM and non-classical DM, which includes amyopathic DM and DM sine dermatitis. DM sine dermatitis is seldom described because of its rarity, making the diagnosis more challenging. We report a case of DM sine dermatitis, a rare phenotype of DM.

Citations

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Effect of Health Status and Heat-Induced Inactivation on the Proteomic Profile of Plasma Rich in Growth Factors Obtained from Donors with Chronic Inflammatory Skin Conditions
Eduardo Anitua, Roberto Tierno, Mikel Azkargorta, Félix Elortza, Mohammad H. Alkhraisat
Biomolecules.2024; 14(7): 763. CrossRef
Anti-MDA5 Antibody-Positive Interstitial Pneumonia with Autoimmune Features Presenting as Amyopathic Hypodermatitic Dermatomyositis: A Case Report
Maria L. Mihailescu, Cuoghi Edens, Mark D. Hoffman
Case Reports in Dermatology.2021; 13(1): 222. CrossRef

A Case of Hypomyopathic Dermatomyositis.: Hyun Tae Kim, Hyun Wook Lee, Byung Jin Kwon, Ji Eun Lee, Dong Ho Oh, Min Su Sohn, Jung Ran Choi; Yeungnam Univ J Med. 2011;28(2):202-205. Published online December 31, 2011; DOI: https://doi.org/10.12701/yujm.2011.28.2.202

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Abstract PDF: Dermatomyositis is a rare and idiopathic inflammatory myopathy with a characteristic cutaneous manifestation. A 62-year-old female complained of polyarthralgia that lasted for many years. She was diagnosed with hypomyopathic dermatomyositis by the typical skin rash associated with dermatomyositis but without muscle involvement such as muscle weakness, elevated level of creatinine phosphokinase and aldolase. Her symptoms improved with treatment of hydroxychloroquine and prednisolone. We experienced a case of hypomyopathic dermatomyositis on 62-year-old female patient and report with review of literatures.

A Case of Dermatomyositis with Secondary Organizing Pneumonia.: Chul Yun Park, Jung Seok Chung, Jin Wook Chung, Choong Ki Lee, Dae Sung Hyun, Jung Yoon Choe; Yeungnam Univ J Med. 2008;25(2):117-123. Published online December 31, 2008; DOI: https://doi.org/10.12701/yujm.2008.25.2.117

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Abstract PDF: Dermatomyositis is characterized by progressive, symmetric, proximal muscle weakness and a nonsuppurative inflammatory myopathy of unknown etiology involving predominantly skeletal muscles. It is also characterized by typical skin lesions. Interstitial lung disease has a poor prognosis when it is associated with dermatomyositis. Organizing pneumonia is a disease in which granulation tissue fills the lumina of terminal and respiratory bronchioles and extends into the distal airspaces. The cryptogenic nature of the process is appreciated in that organizing pneumonia patterns of injury can be seen in secondary forms of the disease (secondary organizing pneumonia). Organizing pneumonia has been reported to occur in 5~10% in dermatomyositis-polymyositis patients. Anti-histidyl tRNA synthetase antibody (anti-Jo-1) is a predictive disease marker that is reported to occur in up to 70% of patients. We describe a 49-year-old male dermatomyositis patient who presented with organizing pneumonia and was found to have negative anti-Jo-1 antibody.

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