Journal of Yeungnam Medical Science

Case Reports

A patient with stress induced cardiomyopathy that occurred after cessation of hormone replacement therapy for panhypopituitarism.: Seoung Wan Nam, Jun Won Lee, Jeong Han Sim, Hyun Sung Pack, Changjo Im, Jung Soo Lim, Sung Gyun Ahn; Yeungnam Univ J Med. 2016;33(2):125-129. Published online December 31, 2016; DOI: https://doi.org/10.12701/yujm.2016.33.2.125

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Abstract PDF: Stress induced cardiomyopathy (SC) is characterized by transient left ventricular (LV) dysfunction in the absence of coronary artery disease. We report on a patient with panhypopituitarism who developed SC resulting from withdrawal of hormonal replacement therapy (HRT). A 52-year-old male visited our hospital for progressively worsening dyspnea. The patient had discontinued HRT 7 days ago, which had been administered for 18 months after transsphenoidal adenomectomy for pituitary macroadenoma. Initial electrocardiogram showed marked sinus bradycardia. Transthoracic echocardiography showed apical ballooning with an LV ejection fraction of 25%. No significant obstructive lesions were observed on coronary angiography. With a clinical diagnosis of SC associated with panhypopituitarism, HRT was restarted, including glucocorticoid and thyroxine, along with standard heart failure management. His LV function had normalized at 2-month follow-up. He remains asymptomatic and administration of beta-blocker and angiotensin converting enzyme inhibitor were discontinued He currently only requires HRT.

Panhypopituitarism due to craniopharyngioma with bilateral slipped capital femoral epiphysis.: Sun Woo Kim, Young Jin Song, Eun Jeong Choi, Dong Hee Han, Hyun Yon Jung, Sung Hoon Yu, Hyung Joon Yoo, Jae Myung Yu; Yeungnam Univ J Med. 2014;31(1):61-64. Published online June 30, 2014; DOI: https://doi.org/10.12701/yujm.2014.31.1.61

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Craniopharyngiomas are rare primary intracranial tumors. Despite their benign histological appearance, they are often associated with an unfavorable prognosis. The typical manifestations upon diagnosis are headache, visual impairment, polyuria/polydypsia, growth retardation, disturbance of pubertal development, and significant weight gain. The treatment options include radical surgery or radiotherapy, or a combination of these modalities. Slipped capital femoral epiphysis (SCFE) is the most common adolescent hip disorder. SCFE occurs when the capital femoral epiphysis displaces posteriorly on the femoral neck at the level of the physis. The etiology of SCFE is thought to be multifactorial and may include obesity, growth surges, and less common endocrine disorders. The related endocrine disorders include hypothyroidism, growth hormone supplementation, hypogonadism, and panhypopituitarism. Reported herein is a case of panhypopituitarism caused by craniopharyngioma combined with SCFE.

Citations

Citations to this article as recorded by

A Case of Slipped Capital Femoral Epiphysis in Association With Craniopharyngioma
Mehran Soleymanha, Ali Karimi, Seyed Mojtaba Mehrdad
Trauma Monthly.2015;[Epub] CrossRef

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