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JYMS : Journal of Yeungnam Medical Science

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1 "Melanosome"
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Case Report
Clear cell sarcoma: 1 case report.
Joon Hyuk Choi, Hae Jeong Choi, Mi Jin Kim, Duk Seop Shin, Kil Ho Cho
Yeungnam Univ J Med. 1999;16(1):108-113.   Published online June 30, 1999
DOI: https://doi.org/10.12701/yujm.1999.16.1.108
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Clear cell sarcoma is a rare soft tissue sarcoma that occurs tendons and aponeuroses, usually of the lower extremities in young adult. The exact histogenesis is not definitely established, We experienced a case of 58 year-old female who presented with a 3.2x2.2cm sized mass located in the subcutaneous tissue on the left lower thigh. The mass was well circumscribed and grayish firm. Two small satellite nodules were also seen. Histologically the tumor was composed of round to fusiform cells with clear or pale eosinophilic cytoplasm and separated into compact nests or short fascicles by delicated fibrous septa. The melanin pigments and hemosiderin were seen. Tumor cells showed positive reaction for S-100 protein and HMB-45. The ultrastructural examination showed abundant mitochondria and melanosomes.

JYMS : Journal of Yeungnam Medical Science