Journal of Yeungnam Medical Science

Case Reports

A Case of Immunoglobulin A Nephropathy in a Patient with Kimura's Disease.: Hye Jung Park, Jae Kyung Kim, Hyun Ju Kim, Kwan Kyu Park, Yoon Sung Bae, Yong Kyu Lee, Beom Seok Kim; Yeungnam Univ J Med. 2013;30(2):149-151. Published online December 31, 2013; DOI: https://doi.org/10.12701/yujm.2013.30.2.149

Abstract PDF: Kimura's disease is an angiolymphoid-proliferative disorder that manifests with benign subcutaneous swelling predominantly in the head and the neck. Kidney involvement, including proteinuria, occurs in 12-16% of patients with the disease, and 60-78% of such cases is nephrotic syndrome. Reported etiologies of nephrotic syndrome in Kimura's disease include membranous glomerulonephritis, mesangial proliferative glomerulonephritis, minimal-change disease, focal segmental glomerulosclerosis, diffuse proliferative glomerulonephritis and immunoglobulin A (IgA) nephropathy. There have been only two case reports of IgA nephropathy in Kimura's disease, in 1998. In this report, we present a third case of IgA nephropathy associated with Kimura's disease.

A Case of Membranoproliferative Glomerulonephritis in a Patient with Type 2 Diabetes Mellitus.: Dong Hyun Kim, Jang Won Lee, Min Suk Jung, Seung Hyun Lee, Byung Cheol Min, Hyun Ju Kim; Yeungnam Univ J Med. 2013;30(2):136-140. Published online December 31, 2013; DOI: https://doi.org/10.12701/yujm.2013.30.2.136

Abstract PDF: Diabetic nephropathy (DN) is a common complication and the leading cause of end-stage renal disease (ESRD) in diabetic patients. The occurrence of non-diabetic renal disease (NDRD) in diabetic patients has been increasingly recognized in recent years. Generally, renal injuries in DN are deemed difficult to reverse, whereas some NDRDs are often treatable and even remittable. Thus, the diagnosis of NDRD in patients with diabetes mellitus (DM) via a kidney biopsy would be significant for its prognosis and therapeutic strategy. According to recent studies, the most common NDRD is IgA nephropathy in type 2 diabetic patients, and some cases of minimal change disease and membranous glomerulonephritis have been reported in Korea. However, membranoproliferative glomerulonephritis (MPGN) is an uncommon condition in diabetic patients. To our knowledge, there has been no case yet of MPGN, except in a child with type 1 DM. We present an unusual case of a 27-year-old woman who had type 2 DM with MPGN, as confirmed via a kidney biopsy.

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