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JYMS : Journal of Yeungnam Medical Science

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Psychiatry and Mental Health
Mega cisterna magna in bipolar mood disorder: a case report
Esra Yazici, Sefanur Kose, Yasemin Gunduz, Elif Merve Kurt, Ahmet Bulent Yazici
J Yeungnam Med Sci. 2022;39(1):58-61.   Published online April 15, 2021
DOI: https://doi.org/10.12701/yujm.2020.00864
  • 21,011 View
  • 151 Download
  • 5 Web of Science
  • 8 Crossref
AbstractAbstract PDF
Mega cisterna magna (MCM), one of the members of the Dandy-Walker complex, is a developmental malformation of the posterior fossa that is larger than 10 mm but morphologically does not affect the vermis and cerebellar hemispheres. Reports of psychiatric disorders associated with this anomaly are rare. We present the case of a patient with MCM who presented with a psychotic manic attack and was diagnosed with bipolar disorder. A 28-year-old female, single housewife, university graduate, presented with irritability, decreased sleep and appetite, distraction, and agitation. The patient also had a delusion of reference. In the clinical follow-up, an increase in energy and an increase in the amount of speech were observed. Her neurological examination was normal, and cranial magnetic resonance imaging revealed an MCM. The relationship and clinical significance of MCM with psychosis and mood disorders have not yet been fully elucidated. It is not known whether this association is accidental or based on etiological commonality. The purpose of this case report is to review the relationship between the cerebellum and psychiatric symptoms and to contribute to the literature.

Citations

Citations to this article as recorded by  
  • Cerebellar vermis and cerebral fissure evaluation in fetuses with isolated mega cisterna magna: a retrospective magnetic resonance imaging study
    Ayşe Ceren Duymuş, Rrezearta Cungu, Özlem Polat Bozbay, Günay Safarova, Mehmet Sedat Durmaz, Aybike Tazegül Pekin, Gökçen Örgül
    BMC Medical Imaging.2026;[Epub]     CrossRef
  • Isolated Mega Cisterna Magna: A Preliminary Study from Eastern Iran
    Masoud Pishjoo, Mohammad Safdari, Zohre Safdari, Mahtab Ghaemi, Daniel Kheradmand, Ali Fathi Jouzdani, Sajjad Saghbdoust
    Asian Journal of Neurosurgery.2025; 20(02): 236.     CrossRef
  • Assessing the role of mega cisterna magna in criminal responsibility: implications for neurocognitive disorders in forensic evaluations
    Gamze Onar, Sena Inal Azizoglu, Ece Büyükakça, Fatih Oncu
    BMC Psychiatry.2025;[Epub]     CrossRef
  • Under‐Interpretation of Neuroimaging Data in Insanity Assessment: A Hidden Risk
    Camilla Frangi, Alexa Schincariol, Pietro Pietrini, Giuseppe Sartori, Stefano Ferracuti, Cristina Scarpazza
    Behavioral Sciences & the Law.2025; 43(5): 530.     CrossRef
  • Morphometric Analysis of the Brainstem and Subarachnoid Cisterns Using Midsagittal MRI: A Retrospective Study
    Hilal Gören, Atakan Kırteke, Nilgün Tuncel Çini
    Uludağ Üniversitesi Tıp Fakültesi Dergisi.2025; 51(3): 577.     CrossRef
  • Radiological characteristics of the posterior fossa of the fetal skull and presentation of a rare case of antenatal screening for Dandy-Walker malformation using antenatal fetal ultrasound and MRI
    Ayoub Amghar, Imane El Abbassi, Jalal Mohammed, Assal Asmaa, Lamrissi Amine, Said Bouhya
    International Journal of Surgery Case Reports.2024;[Epub]     CrossRef
  • Tic-Related Obsessive–Compulsive and Eating Disorders in Dandy–Walker Variant: A Case Report and Systematic Reappraisal of Psychiatric Profiles
    Riccardo Bortoletto, Anna Candolo, Alessandra Nicotra, Luana Saetti, Laura Perini, Matteo Balestrieri, Marco Colizzi, Carla Comacchio
    Brain Sciences.2024; 14(4): 362.     CrossRef
  • Benzodiazepines for Treatment-Resistant Major Depressive Disorder and Obsessive-Compulsive Disorder With Comorbid Mega Cisterna Magna
    Arifah Ismail, Asrenee Ab Razak, Khairil Amir Sayuti, Picholas Kian Ann Phoa
    Cureus.2023;[Epub]     CrossRef
Case Report
Neurology
A Case of Severe Hypoglycemic Encephalopathy with Extensive Brain Lesions in Non-diabetics and Alcoholism.
Chang Hun Bin, Min Su Park, Se Jin Lee
Yeungnam Univ J Med. 2010;27(1):37-41.   Published online June 30, 2010
DOI: https://doi.org/10.12701/yujm.2010.27.1.37
  • 3,014 View
  • 16 Download
  • 1 Crossref
AbstractAbstract PDF
Hypoglycemic encephalopathy is a rare problem among diabetic patients who are receiving treatment with insulin or other glucose-lowering drugs. The MRIs of patients with hypoglycemic encephalopathy commonly show scattered lesions in the cerebral cortex, hippocampus and basal ganglia, but lesions in the cerebellum or brain stem are extremely rare. A 44-year-old alcoholic woman without diabetes was admitted with a semicomatose mentality and seizure with severe hypoglycemic encephalopathy with extensive brain lesions seen on MRI at the middle cerebellar peduncle and midbrain, as well as in the other brain areas.

Citations

Citations to this article as recorded by  
  • Consideration of Prognostic Factors in Hypoglycemic Encephalopathy
    Ik-Kwon Seo, Woo-Ik Choi, Sang-Chan Jin, Hyuk-Won Chang
    Korean Journal of Critical Care Medicine.2012; 27(4): 209.     CrossRef

JYMS : Journal of Yeungnam Medical Science
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