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JYMS : Journal of Yeungnam Medical Science

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HOME > J Yeungnam Med Sci > Volume 23(2); 2006 > Article
Case Report Two Cases of Alopecia Totalis treated with Diphenylcyclopropenone (DPCP) Immunotherapy.
Seok Ki Moon, Young Min Shin, Chan Woo Kim, Dong Hoon Shin, Jong Soo Choi, Ki Hong Kim
Journal of Yeungnam Medical Science 2006;23(2):232-239
Published online: December 31, 2006
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Department of Dermatology, College of Medicine, Yeungnam University, Daegu, Korea.

Treatments for alopecia areata include topical corticosteroid treatment, corticosteroid intralesional injection, systemic corticosteroid treatment, PUVA(psoralen-UVA) and topical immunotherapy. The therapeutic effects are variable. Alopecia totalis is hard to treat completely. Topical immunotherapy with dinitrochlorobenzene (DNCB), squaric acid dibutyl ester (SADBE) or diphenylcyclopropenone (diphencyprone, DPCP) represents the most accepted therapeutic modality for the treatment of extensive alopecia areata. We report two cases of alopecia totalis treated with DPCP. After DPCP treatment, total scalp hair was completely recovered.

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